Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency prof...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BioMed Central
2015-12-01
|
| Series: | Genomics & Informatics |
| Subjects: | |
| Online Access: | http://genominfo.org/upload/pdf/gni-13-152.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832573941681487872 |
|---|---|
| author | Heather Lent Kyung-Eun Lee Hyun-Seok Park |
| author_facet | Heather Lent Kyung-Eun Lee Hyun-Seok Park |
| author_sort | Heather Lent |
| collection | DOAJ |
| description | Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function. |
| format | Article |
| id | doaj-art-f6a0be6b4b7844c5bc5475b384aff5af |
| institution | Kabale University |
| issn | 1598-866X 2234-0742 |
| language | English |
| publishDate | 2015-12-01 |
| publisher | BioMed Central |
| record_format | Article |
| series | Genomics & Informatics |
| spelling | doaj-art-f6a0be6b4b7844c5bc5475b384aff5af2025-02-02T02:09:28ZengBioMed CentralGenomics & Informatics1598-866X2234-07422015-12-0113415215510.5808/GI.2015.13.4.152146Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical PerspectiveHeather Lent0Kyung-Eun Lee1Hyun-Seok Park2Bioinformatics Laboratory, School of Engineering, Ewha Womans University, Seoul 03760, Korea.Bioinformatics Laboratory, School of Engineering, Ewha Womans University, Seoul 03760, Korea.Bioinformatics Laboratory, School of Engineering, Ewha Womans University, Seoul 03760, Korea.Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function.http://genominfo.org/upload/pdf/gni-13-152.pdfchromatin stateepigeneticsepigenomicsgenetic promoter regions |
| spellingShingle | Heather Lent Kyung-Eun Lee Hyun-Seok Park Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective Genomics & Informatics chromatin state epigenetics epigenomics genetic promoter regions |
| title | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
| title_full | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
| title_fullStr | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
| title_full_unstemmed | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
| title_short | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
| title_sort | building the frequency profile of the core promoter element patterns in the three chromhmm promoter states at 200bp intervals a statistical perspective |
| topic | chromatin state epigenetics epigenomics genetic promoter regions |
| url | http://genominfo.org/upload/pdf/gni-13-152.pdf |
| work_keys_str_mv | AT heatherlent buildingthefrequencyprofileofthecorepromoterelementpatternsinthethreechromhmmpromoterstatesat200bpintervalsastatisticalperspective AT kyungeunlee buildingthefrequencyprofileofthecorepromoterelementpatternsinthethreechromhmmpromoterstatesat200bpintervalsastatisticalperspective AT hyunseokpark buildingthefrequencyprofileofthecorepromoterelementpatternsinthethreechromhmmpromoterstatesat200bpintervalsastatisticalperspective |