Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes
Immune suppression after oncologic surgery is a common phenomenon. Several studies have demonstrated that it is associated with poor survival owing to cancer progression. Immunotherapy, especially NK cell transfer therapy, is an attractive alternative because current methodologies to isolate, genera...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Scientifica |
| Online Access: | http://dx.doi.org/10.1155/2015/732438 |
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| _version_ | 1832549969140121600 |
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| author | Juan P. Cata Claudius Conrad Katy Rezvani |
| author_facet | Juan P. Cata Claudius Conrad Katy Rezvani |
| author_sort | Juan P. Cata |
| collection | DOAJ |
| description | Immune suppression after oncologic surgery is a common phenomenon. Several studies have demonstrated that it is associated with poor survival owing to cancer progression. Immunotherapy, especially NK cell transfer therapy, is an attractive alternative because current methodologies to isolate, generate, and expand NK cells have shown good safety profiles in current active investigations. We believe that the use of NK cell transfer therapy in the context of postoperative minimal residual disease deserves significant investigation. |
| format | Article |
| id | doaj-art-f69c714225c14bf5b0bd8096d4f21408 |
| institution | Kabale University |
| issn | 2090-908X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Scientifica |
| spelling | doaj-art-f69c714225c14bf5b0bd8096d4f214082025-02-03T06:08:16ZengWileyScientifica2090-908X2015-01-01201510.1155/2015/732438732438Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic OutcomesJuan P. Cata0Claudius Conrad1Katy Rezvani2Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAImmune suppression after oncologic surgery is a common phenomenon. Several studies have demonstrated that it is associated with poor survival owing to cancer progression. Immunotherapy, especially NK cell transfer therapy, is an attractive alternative because current methodologies to isolate, generate, and expand NK cells have shown good safety profiles in current active investigations. We believe that the use of NK cell transfer therapy in the context of postoperative minimal residual disease deserves significant investigation.http://dx.doi.org/10.1155/2015/732438 |
| spellingShingle | Juan P. Cata Claudius Conrad Katy Rezvani Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes Scientifica |
| title | Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes |
| title_full | Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes |
| title_fullStr | Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes |
| title_full_unstemmed | Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes |
| title_short | Potential Use of Natural Killer Cell Transfer Therapy in the Perioperative Period to Improve Oncologic Outcomes |
| title_sort | potential use of natural killer cell transfer therapy in the perioperative period to improve oncologic outcomes |
| url | http://dx.doi.org/10.1155/2015/732438 |
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