Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View
We have advanced considerably in the past 2 to 3 years in understanding the molecular mechanisms of consolidation, retrieval, and extinction of memories, particularly of fear memory. This advance was mainly due to pharmacological studies in many laboratories using localized brain injections of molec...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2004-01-01
|
| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/NP.2004.159 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559940803231744 |
|---|---|
| author | Iván Izquierdo Martín Cammarota Jorge H. Medina Lia R. M. Bevilaqua |
| author_facet | Iván Izquierdo Martín Cammarota Jorge H. Medina Lia R. M. Bevilaqua |
| author_sort | Iván Izquierdo |
| collection | DOAJ |
| description | We have advanced considerably in the past
2 to 3 years in understanding the molecular
mechanisms of consolidation, retrieval, and
extinction of memories, particularly of fear
memory. This advance was mainly due to
pharmacological studies in many laboratories
using localized brain injections of molecularly
specific substances. One area in which significant
advances have been made is in understanding
that many different brain structures are
involved in different memories, and that often
several brain regions are involved in processing
the same memory. These regions can cooperate
or compete with each other, depending on
circumstances that are beginning to be
identified quite clearly. Another aspect in
which major advances were made was retrieval
and post-retrieval events, especially extinction,
pointing to new therapeutic approaches to fearmotivated
mental disorders. |
| format | Article |
| id | doaj-art-f669894649f74327b6289cc4522af383 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2004-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-f669894649f74327b6289cc4522af3832025-02-03T01:28:50ZengWileyNeural Plasticity2090-59041687-54432004-01-01113-415918910.1155/NP.2004.159Pharmacological Findings on the Biochemical Bases of Memory Processes: A General ViewIván Izquierdo0Martín Cammarota1Jorge H. Medina2Lia R. M. Bevilaqua3Centro de Memoria, Departamento de Bioquímica, Instituto de Ciencias Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2600-anexo (90035-003), Porto Alegre, RS, BrazilCentro de Memoria, Departamento de Bioquímica, Instituto de Ciencias Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2600-anexo (90035-003), Porto Alegre, RS, BrazilCentro de Memoria, Departamento de Bioquímica, Instituto de Ciencias Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2600-anexo (90035-003), Porto Alegre, RS, BrazilCentro de Memoria, Departamento de Bioquímica, Instituto de Ciencias Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2600-anexo (90035-003), Porto Alegre, RS, BrazilWe have advanced considerably in the past 2 to 3 years in understanding the molecular mechanisms of consolidation, retrieval, and extinction of memories, particularly of fear memory. This advance was mainly due to pharmacological studies in many laboratories using localized brain injections of molecularly specific substances. One area in which significant advances have been made is in understanding that many different brain structures are involved in different memories, and that often several brain regions are involved in processing the same memory. These regions can cooperate or compete with each other, depending on circumstances that are beginning to be identified quite clearly. Another aspect in which major advances were made was retrieval and post-retrieval events, especially extinction, pointing to new therapeutic approaches to fearmotivated mental disorders.http://dx.doi.org/10.1155/NP.2004.159 |
| spellingShingle | Iván Izquierdo Martín Cammarota Jorge H. Medina Lia R. M. Bevilaqua Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View Neural Plasticity |
| title | Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View |
| title_full | Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View |
| title_fullStr | Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View |
| title_full_unstemmed | Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View |
| title_short | Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View |
| title_sort | pharmacological findings on the biochemical bases of memory processes a general view |
| url | http://dx.doi.org/10.1155/NP.2004.159 |
| work_keys_str_mv | AT ivanizquierdo pharmacologicalfindingsonthebiochemicalbasesofmemoryprocessesageneralview AT martincammarota pharmacologicalfindingsonthebiochemicalbasesofmemoryprocessesageneralview AT jorgehmedina pharmacologicalfindingsonthebiochemicalbasesofmemoryprocessesageneralview AT liarmbevilaqua pharmacologicalfindingsonthebiochemicalbasesofmemoryprocessesageneralview |