Pharmacological Findings on the Biochemical Bases of Memory Processes: A General View
We have advanced considerably in the past 2 to 3 years in understanding the molecular mechanisms of consolidation, retrieval, and extinction of memories, particularly of fear memory. This advance was mainly due to pharmacological studies in many laboratories using localized brain injections of molec...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2004-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/NP.2004.159 |
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Summary: | We have advanced considerably in the past
2 to 3 years in understanding the molecular
mechanisms of consolidation, retrieval, and
extinction of memories, particularly of fear
memory. This advance was mainly due to
pharmacological studies in many laboratories
using localized brain injections of molecularly
specific substances. One area in which significant
advances have been made is in understanding
that many different brain structures are
involved in different memories, and that often
several brain regions are involved in processing
the same memory. These regions can cooperate
or compete with each other, depending on
circumstances that are beginning to be
identified quite clearly. Another aspect in
which major advances were made was retrieval
and post-retrieval events, especially extinction,
pointing to new therapeutic approaches to fearmotivated
mental disorders. |
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ISSN: | 2090-5904 1687-5443 |