Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment
Molecular imaging technologies have significantly transformed cancer research and clinical practice, offering valuable tools for visualizing and understanding the complex tumor immune microenvironment. These technologies allow for the non-invasive examination of key components within the tumor immun...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1518555/full |
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| author | Xiang Wang Xiang Wang Weifen Shen Weifen Shen Lingjun Yao Lingjun Yao Chao Li Chao Li Huiming You Huiming You Duancheng Guo Duancheng Guo |
| author_facet | Xiang Wang Xiang Wang Weifen Shen Weifen Shen Lingjun Yao Lingjun Yao Chao Li Chao Li Huiming You Huiming You Duancheng Guo Duancheng Guo |
| author_sort | Xiang Wang |
| collection | DOAJ |
| description | Molecular imaging technologies have significantly transformed cancer research and clinical practice, offering valuable tools for visualizing and understanding the complex tumor immune microenvironment. These technologies allow for the non-invasive examination of key components within the tumor immune microenvironment, including immune cells, cytokines, and stromal cells, providing crucial insights into tumor biology and treatment responses. This paper reviews the latest advancements in molecular imaging, with a focus on its applications in assessing interactions within the tumor immune microenvironment. Additionally, the challenges faced by molecular imaging technologies are discussed, such as the need for highly sensitive and specific imaging agents, issues with data integration, and difficulties in clinical translation. The future outlook emphasizes the potential of molecular imaging to enhance personalized cancer treatment through the integration of artificial intelligence and the development of novel imaging probes. Addressing these challenges is essential to fully realizing the potential of molecular imaging in improving cancer diagnosis, treatment, and patient outcomes. |
| format | Article |
| id | doaj-art-f66533230f1542899b0a336566597718 |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-f66533230f1542899b0a3365665977182025-01-22T07:12:56ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-01-011610.3389/fimmu.2025.15185551518555Current status and future prospects of molecular imaging in targeting the tumor immune microenvironmentXiang Wang0Xiang Wang1Weifen Shen2Weifen Shen3Lingjun Yao4Lingjun Yao5Chao Li6Chao Li7Huiming You8Huiming You9Duancheng Guo10Duancheng Guo11Department of Radiology, First People’s Hospital of Linping District, Hangzhou, ChinaThe Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, First People’s Hospital of Linping District, Hangzhou, ChinaThe Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, First People’s Hospital of Linping District, Hangzhou, ChinaThe Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, First People’s Hospital of Linping District, Hangzhou, ChinaThe Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, First People’s Hospital of Linping District, Hangzhou, ChinaThe Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, ChinaCancer Institute, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, ChinaMolecular imaging technologies have significantly transformed cancer research and clinical practice, offering valuable tools for visualizing and understanding the complex tumor immune microenvironment. These technologies allow for the non-invasive examination of key components within the tumor immune microenvironment, including immune cells, cytokines, and stromal cells, providing crucial insights into tumor biology and treatment responses. This paper reviews the latest advancements in molecular imaging, with a focus on its applications in assessing interactions within the tumor immune microenvironment. Additionally, the challenges faced by molecular imaging technologies are discussed, such as the need for highly sensitive and specific imaging agents, issues with data integration, and difficulties in clinical translation. The future outlook emphasizes the potential of molecular imaging to enhance personalized cancer treatment through the integration of artificial intelligence and the development of novel imaging probes. Addressing these challenges is essential to fully realizing the potential of molecular imaging in improving cancer diagnosis, treatment, and patient outcomes.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1518555/fullmolecular imagingtumor microenvironmenttumor immuneimmunotherapyimmune cells |
| spellingShingle | Xiang Wang Xiang Wang Weifen Shen Weifen Shen Lingjun Yao Lingjun Yao Chao Li Chao Li Huiming You Huiming You Duancheng Guo Duancheng Guo Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment Frontiers in Immunology molecular imaging tumor microenvironment tumor immune immunotherapy immune cells |
| title | Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment |
| title_full | Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment |
| title_fullStr | Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment |
| title_full_unstemmed | Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment |
| title_short | Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment |
| title_sort | current status and future prospects of molecular imaging in targeting the tumor immune microenvironment |
| topic | molecular imaging tumor microenvironment tumor immune immunotherapy immune cells |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1518555/full |
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