Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges
Stress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autolog...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2016/7060975 |
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| _version_ | 1832545824715833344 |
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| author | Shukui Zhou Kaile Zhang Anthony Atala Oula Khoury Sean V. Murphy Weixin Zhao Qiang Fu |
| author_facet | Shukui Zhou Kaile Zhang Anthony Atala Oula Khoury Sean V. Murphy Weixin Zhao Qiang Fu |
| author_sort | Shukui Zhou |
| collection | DOAJ |
| description | Stress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autologous stem cells as well as many studies describing their applications for the treatment of SUI. In this paper, we review recent publications and clinical trials investigating the applications of several stem cell types as potential treatments for SUI and the underlying challenges of such therapy. |
| format | Article |
| id | doaj-art-f6531846df1d40ccb3b41b874605adc4 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-f6531846df1d40ccb3b41b874605adc42025-02-03T07:24:41ZengWileyStem Cells International1687-966X1687-96782016-01-01201610.1155/2016/70609757060975Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and ChallengesShukui Zhou0Kaile Zhang1Anthony Atala2Oula Khoury3Sean V. Murphy4Weixin Zhao5Qiang Fu6Department of Urology, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai, ChinaDepartment of Urology, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai, ChinaWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USAWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USAWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USAWake Forest Institute for Regenerative Medicine, Winston Salem, NC, USADepartment of Urology, Affiliated Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai, ChinaStress urinary incontinence (SUI) is a common urinary system disease that mostly affects women. Current treatments still do not solve the critical problem of urethral sphincter dysfunction. In recent years, there have been major developments in techniques to obtain, culture, and characterize autologous stem cells as well as many studies describing their applications for the treatment of SUI. In this paper, we review recent publications and clinical trials investigating the applications of several stem cell types as potential treatments for SUI and the underlying challenges of such therapy.http://dx.doi.org/10.1155/2016/7060975 |
| spellingShingle | Shukui Zhou Kaile Zhang Anthony Atala Oula Khoury Sean V. Murphy Weixin Zhao Qiang Fu Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges Stem Cells International |
| title | Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges |
| title_full | Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges |
| title_fullStr | Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges |
| title_full_unstemmed | Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges |
| title_short | Stem Cell Therapy for Treatment of Stress Urinary Incontinence: The Current Status and Challenges |
| title_sort | stem cell therapy for treatment of stress urinary incontinence the current status and challenges |
| url | http://dx.doi.org/10.1155/2016/7060975 |
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