Hypernatremia in patients with neurological conditions in critical state
<p><strong>Background:</strong> sodium disorders are the most common and least understood in patients with acute brain injury due to the major role played by the central nervous system in regulating sodium and water homeostasis, which can lead to serious complications and adverse o...
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2023-05-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/5697 |
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| author | David Wilfredo Suàrez Prieto Mairen Pèrez Fuentes Elaine Teresa Gutièrrez Pèrez |
| author_facet | David Wilfredo Suàrez Prieto Mairen Pèrez Fuentes Elaine Teresa Gutièrrez Pèrez |
| author_sort | David Wilfredo Suàrez Prieto |
| collection | DOAJ |
| description | <p><strong>Background:</strong> sodium disorders are the most common and least understood in patients with acute brain injury due to the major role played by the central nervous system in regulating sodium and water homeostasis, which can lead to serious complications and adverse outcomes, including death.<br /><strong>Objective:</strong> to determine the hypernatremia contribution to mortality in patients with neurological conditions in critical state. <br /><strong>Methods:</strong> longitudinal analytical observational study on 55 patients who were admitted to the acute care units at the Arnaldo Milián Castro University Hospital, between October 2020 and May 2022, regardless of the plasma sodium value upon admission to the service, as well as during their stay in the critical care units. Univariate and bivariate statistical methods were used in data analysis. <br /><strong>Results:</strong> the average age was 60 ± 16 years. The most relevant diagnoses were intraparenchymal hemorrhage (56.37%), head trauma, and ischemic stroke (both 30%). Plasma sodium concentrations showed significant differences (pX2= 0.000), with the highest average at 24 hours of admission (174.2 ± 133.6) and the lowest at the 5th day (102.9 ± 72.9). There was a significant correlation between plasma sodium concentrations at admission, 24h and 72h with the state at discharge. In the individual bivariate analysis by period, there was only a significant relationship after 24 hours. In this period, hypernatremia contributed 1.78 times more to mortality than in those who did not have elevated sodium (OR=1.78 with CI: 1,39-3,4).<br /><strong>Conclusions:</strong> hypernatremia in critically ill patients with neurological conditions is associated with increased mortality.</p> |
| format | Article |
| id | doaj-art-f64f003bd70344108229815c21950c34 |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2023-05-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-f64f003bd70344108229815c21950c342025-01-30T21:29:00ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2023-05-012136136232304Hypernatremia in patients with neurological conditions in critical stateDavid Wilfredo Suàrez Prieto0Mairen Pèrez Fuentes1Elaine Teresa Gutièrrez Pèrez2Hospital Universitario Clínico Quirúrgico Arnaldo Milián. Villa Clara. Cuba.Hospital Universitario Clínico Quirúrgico Arnaldo Milián. Villa Clara. Cuba.Hospital Universitario Clínico Quirúrgico Arnaldo Milián. Villa Clara. Cuba.<p><strong>Background:</strong> sodium disorders are the most common and least understood in patients with acute brain injury due to the major role played by the central nervous system in regulating sodium and water homeostasis, which can lead to serious complications and adverse outcomes, including death.<br /><strong>Objective:</strong> to determine the hypernatremia contribution to mortality in patients with neurological conditions in critical state. <br /><strong>Methods:</strong> longitudinal analytical observational study on 55 patients who were admitted to the acute care units at the Arnaldo Milián Castro University Hospital, between October 2020 and May 2022, regardless of the plasma sodium value upon admission to the service, as well as during their stay in the critical care units. Univariate and bivariate statistical methods were used in data analysis. <br /><strong>Results:</strong> the average age was 60 ± 16 years. The most relevant diagnoses were intraparenchymal hemorrhage (56.37%), head trauma, and ischemic stroke (both 30%). Plasma sodium concentrations showed significant differences (pX2= 0.000), with the highest average at 24 hours of admission (174.2 ± 133.6) and the lowest at the 5th day (102.9 ± 72.9). There was a significant correlation between plasma sodium concentrations at admission, 24h and 72h with the state at discharge. In the individual bivariate analysis by period, there was only a significant relationship after 24 hours. In this period, hypernatremia contributed 1.78 times more to mortality than in those who did not have elevated sodium (OR=1.78 with CI: 1,39-3,4).<br /><strong>Conclusions:</strong> hypernatremia in critically ill patients with neurological conditions is associated with increased mortality.</p>http://medisur.sld.cu/index.php/medisur/article/view/5697hipernatremiahemorragia cerebralhemorragia cerebral intraventricular, accidente cerebrovascular trombóticomortalidad |
| spellingShingle | David Wilfredo Suàrez Prieto Mairen Pèrez Fuentes Elaine Teresa Gutièrrez Pèrez Hypernatremia in patients with neurological conditions in critical state Medisur hipernatremia hemorragia cerebral hemorragia cerebral intraventricular, accidente cerebrovascular trombótico mortalidad |
| title | Hypernatremia in patients with neurological conditions in critical state |
| title_full | Hypernatremia in patients with neurological conditions in critical state |
| title_fullStr | Hypernatremia in patients with neurological conditions in critical state |
| title_full_unstemmed | Hypernatremia in patients with neurological conditions in critical state |
| title_short | Hypernatremia in patients with neurological conditions in critical state |
| title_sort | hypernatremia in patients with neurological conditions in critical state |
| topic | hipernatremia hemorragia cerebral hemorragia cerebral intraventricular, accidente cerebrovascular trombótico mortalidad |
| url | http://medisur.sld.cu/index.php/medisur/article/view/5697 |
| work_keys_str_mv | AT davidwilfredosuarezprieto hypernatremiainpatientswithneurologicalconditionsincriticalstate AT mairenperezfuentes hypernatremiainpatientswithneurologicalconditionsincriticalstate AT elaineteresagutierrezperez hypernatremiainpatientswithneurologicalconditionsincriticalstate |