Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome
Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the “epide...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2012/175245 |
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| author | Tiziana Di Chiara Christiano Argano Salvatore Corrao Rosario Scaglione Giuseppe Licata |
| author_facet | Tiziana Di Chiara Christiano Argano Salvatore Corrao Rosario Scaglione Giuseppe Licata |
| author_sort | Tiziana Di Chiara |
| collection | DOAJ |
| description | Metabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the “epidemic” obesity, with a considerable impact on the global incidence of cardiovascular disease and type 2 diabetes. At present, there is a growing interest on the role of visceral fat accumulation in the occurrence of MetS. In this review, the effects of adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of the MetS have been also emphasized. Accordingly, the “hypoadiponectinemia” has been proposed as the most interesting new hypothesis to explain the pathophysiology of MetS. |
| format | Article |
| id | doaj-art-f6176b0dd2094abda96015c32c56a4a5 |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-f6176b0dd2094abda96015c32c56a4a52025-02-03T07:24:21ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322012-01-01201210.1155/2012/175245175245Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic SyndromeTiziana Di Chiara0Christiano Argano1Salvatore Corrao2Rosario Scaglione3Giuseppe Licata4Dipartimento Biomedico di Medicina Interna e Specialistica, Università Degli Studi di Palermo, Piazza delle Cliniche 2, 90127 Palermo, ItalyDivisione di Medicina Interna, Fondazione Istituto San Raffaele Giglio, Contrada Pietra Pollastra, 90015 Cefalù, Palermo, ItalyDipartimento Biomedico di Medicina Interna e Specialistica, Università Degli Studi di Palermo, Piazza delle Cliniche 2, 90127 Palermo, ItalyDipartimento Biomedico di Medicina Interna e Specialistica, Università Degli Studi di Palermo, Piazza delle Cliniche 2, 90127 Palermo, ItalyDipartimento Biomedico di Medicina Interna e Specialistica, Università Degli Studi di Palermo, Piazza delle Cliniche 2, 90127 Palermo, ItalyMetabolic syndrome (MetS) represents a combination of cardiometabolic risk factors, including visceral obesity, glucose intolerance or type 2 diabetes, elevated triglycerides, reduced HDL cholesterol, and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the “epidemic” obesity, with a considerable impact on the global incidence of cardiovascular disease and type 2 diabetes. At present, there is a growing interest on the role of visceral fat accumulation in the occurrence of MetS. In this review, the effects of adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of the MetS have been also emphasized. Accordingly, the “hypoadiponectinemia” has been proposed as the most interesting new hypothesis to explain the pathophysiology of MetS.http://dx.doi.org/10.1155/2012/175245 |
| spellingShingle | Tiziana Di Chiara Christiano Argano Salvatore Corrao Rosario Scaglione Giuseppe Licata Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome Journal of Nutrition and Metabolism |
| title | Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome |
| title_full | Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome |
| title_fullStr | Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome |
| title_full_unstemmed | Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome |
| title_short | Hypoadiponectinemia: A Link between Visceral Obesity and Metabolic Syndrome |
| title_sort | hypoadiponectinemia a link between visceral obesity and metabolic syndrome |
| url | http://dx.doi.org/10.1155/2012/175245 |
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