NHE7 drives endometrial cancer progression by delaying senescence through cAMP/CREB/GRIN2B axis-mediated Ca²⁺ influx

NHE7 drives endometrial cancer progression by delaying senescence through cAMP/CREB/GRIN2B axis-mediated Ca²⁺ influx

Abstract Endometrial cancer (EC) remains a lethal gynecological malignancy with limited therapeutic options owing to unresolved pathogenesis. Cellular senescence acts as a key barrier against tumorigenesis in cancer cells, thus investigating its role in EC progression represents a pivotal research a...

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Bibliographic Details
Main Authors:	Shizhou Yang, Tao Shen, Minghua Yu, Tingting Wu, Linhua Qian, Wu Liu, Ting Wang, Xiufeng Huang
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-025-08296-1
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