Mesenchymal Stem Cells with Simultaneous Overexpression of GPX3 and CD47 for the Treatment of Drug-Induced Acute Liver Injury

Mesenchymal Stem Cells with Simultaneous Overexpression of GPX3 and CD47 for the Treatment of Drug-Induced Acute Liver Injury

The liver, as the largest metabolic and detoxification organ in mammals, metabolizes approximately 80–90% of drugs. However, drug-induced liver injury (DILI) is common and driven by factors such as individual variability, differences in liver metabolism, and improper drug use. Mesenchymal stem cells...

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Bibliographic Details
Main Authors: Yuanxiang Jing, Balun Li, Aili Aierken, Zengyu Zhang, Dongyao Han, Zixi Lin, Jiaqi Gao, Hongkai Tian, Jinlian Hua
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Veterinary Sciences
Subjects:
mesenchymal stem cells (MSCs)
GPX3
CD47
drug-induced liver injury
Online Access:https://www.mdpi.com/2306-7381/12/2/149
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