Case Report: Avoiding misdiagnosis in amyloidosis—navigating transthyretin genopositivity and monoclonal gammopathy in a patient with advanced heart failure and spinal stenosis

Case Report: Avoiding misdiagnosis in amyloidosis—navigating transthyretin genopositivity and monoclonal gammopathy in a patient with advanced heart failure and spinal stenosis

BackgroundA 63-year-old Black woman presented with progressive exertional dyspnea and chronic lower back pain. The course and findings in her case are instructive.Case reportFamily history was notable for cardiac deaths. An echocardiogram demonstrated ventricular wall thickening with diastolic dysfu...

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Main Authors: Xia Wu, Denis Toskic, Ping Zhou, Stephanie Scalia, Xun Ma, Parva Bhatt, Teresa Fogaren, Monika Pilichowska, Knarik Arkun, Jainith Patel, Ron I. Riesenburger, Daniel P. Larson, Raymond L. Comenzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
ATTR amyloidosis
AL amyloidosis
cardiac amyloidosis
ligamentum flavum (LF)
differential diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1479676/full
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