The Impact of Misdiagnosing Celiac Disease at a Referral Centre
In the past few years, the number of celiac disease diagnoses not confirmed at the Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, a tertiary referral centre, was particularly high. Therefore, a decision was made to investigate the reasons why these diagnoses were wrong and by whom they had b...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2009/258041 |
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| author | Federico Biagi Paola I Bianchi Jonia Campanella Giovanni Zanellati Gino R Corazza |
| author_facet | Federico Biagi Paola I Bianchi Jonia Campanella Giovanni Zanellati Gino R Corazza |
| author_sort | Federico Biagi |
| collection | DOAJ |
| description | In the past few years, the number of celiac disease diagnoses not confirmed at the Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, a tertiary referral centre, was particularly high. Therefore, a decision was made to investigate the reasons why these diagnoses were wrong and by whom they had been made. The clinical histories of all celiac patients referred to the centre were re-evaluated. Between December 1998 and January 2007, 614 patients who were diagnosed at other institutions and presumed to be affected by celiac disease attended the tertiary referral outpatient clinic. The histological and serological results allowed for confirmation the diagnosis in 434 patients. In the remaining 180 patients, the initial diagnosis of celiac disease could not be confirmed; therefore, the patients were re-investigated. After re-evaluation, the diagnosis of celiac disease was confirmed in only 61 of these 180 cases. The reasons for incorrect initial diagnosis were analyzed. A mere 80% correct diagnosis rate is a very disappointing result. Although it should be obvious that celiac disease must be investigated with duodenal biopsies and celiac antibody testing, this well-known strategy is not always followed, probably resulting in an incorrect diagnosis. |
| format | Article |
| id | doaj-art-f5d8a340d1004904be28c45ca4bd5ddf |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-f5d8a340d1004904be28c45ca4bd5ddf2025-02-03T06:08:12ZengWileyCanadian Journal of Gastroenterology0835-79002009-01-0123854354510.1155/2009/258041The Impact of Misdiagnosing Celiac Disease at a Referral CentreFederico Biagi0Paola I Bianchi1Jonia Campanella2Giovanni Zanellati3Gino R Corazza4Coeliac Centre/First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyCoeliac Centre/First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyCoeliac Centre/First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyCoeliac Centre/First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyCoeliac Centre/First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, ItalyIn the past few years, the number of celiac disease diagnoses not confirmed at the Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, a tertiary referral centre, was particularly high. Therefore, a decision was made to investigate the reasons why these diagnoses were wrong and by whom they had been made. The clinical histories of all celiac patients referred to the centre were re-evaluated. Between December 1998 and January 2007, 614 patients who were diagnosed at other institutions and presumed to be affected by celiac disease attended the tertiary referral outpatient clinic. The histological and serological results allowed for confirmation the diagnosis in 434 patients. In the remaining 180 patients, the initial diagnosis of celiac disease could not be confirmed; therefore, the patients were re-investigated. After re-evaluation, the diagnosis of celiac disease was confirmed in only 61 of these 180 cases. The reasons for incorrect initial diagnosis were analyzed. A mere 80% correct diagnosis rate is a very disappointing result. Although it should be obvious that celiac disease must be investigated with duodenal biopsies and celiac antibody testing, this well-known strategy is not always followed, probably resulting in an incorrect diagnosis.http://dx.doi.org/10.1155/2009/258041 |
| spellingShingle | Federico Biagi Paola I Bianchi Jonia Campanella Giovanni Zanellati Gino R Corazza The Impact of Misdiagnosing Celiac Disease at a Referral Centre Canadian Journal of Gastroenterology |
| title | The Impact of Misdiagnosing Celiac Disease at a Referral Centre |
| title_full | The Impact of Misdiagnosing Celiac Disease at a Referral Centre |
| title_fullStr | The Impact of Misdiagnosing Celiac Disease at a Referral Centre |
| title_full_unstemmed | The Impact of Misdiagnosing Celiac Disease at a Referral Centre |
| title_short | The Impact of Misdiagnosing Celiac Disease at a Referral Centre |
| title_sort | impact of misdiagnosing celiac disease at a referral centre |
| url | http://dx.doi.org/10.1155/2009/258041 |
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