Targeting ocular tissues with intravenously administered aptamers selected by in vivo SELEX

Targeting ocular tissues with intravenously administered aptamers selected by in vivo SELEX

Ocular diseases create a significant economic burden and decrease in quality of life worldwide. Drugs and carrier molecules that penetrate ocular tissues after intravenous administration are needed for more efficient and patient-friendly treatment of ocular diseases. Here, ocular barrier-penetrating...

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Bibliographic Details
Main Authors: Sonja Korhonen, Katja Stenberg, Umair Seemab, Piia Bartos, Katariina Mäkiniemi, Jørgen Kjems, Daniel Miotto Dupont, Astrid Subrizi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Delivery Strategies
SELEX
aptamers
eye
ocular targeting
intravenous administration
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253124002397
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