The role of platelet-rich plasma in biomedicine: A comprehensive overview
Summary: Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice. This blood derivative, enriched with platelet components, has shown great potential for promoting tissue repair and regeneration. Its wide range of...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224029328 |
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| author | Zhixin Zhang Peng Liu Xinmiao Xue Zhiyu Zhang Li Wang Yvke Jiang Chi Zhang Hanwen Zhou Shuhan Lv Weidong Shen Shiming Yang Fangyuan Wang |
| author_facet | Zhixin Zhang Peng Liu Xinmiao Xue Zhiyu Zhang Li Wang Yvke Jiang Chi Zhang Hanwen Zhou Shuhan Lv Weidong Shen Shiming Yang Fangyuan Wang |
| author_sort | Zhixin Zhang |
| collection | DOAJ |
| description | Summary: Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice. This blood derivative, enriched with platelet components, has shown great potential for promoting tissue repair and regeneration. Its wide range of applications and the presence of anti-inflammatory and growth-promoting factors make it a valuable tool in the field of biomedicine. The exploration of PRP in clinical settings has been gaining momentum. Despite its cost-effectiveness, safety, and therapeutic efficacy, the widespread clinical adoption of PRP has been hindered by the absence of consistent preparation standards and standardized treatment protocols. This article provides a comprehensive analysis of the clinical uses, physiological roles, molecular mechanisms, and preparation techniques of PRP in biomedicine. The aim is to offer a thorough understanding of the potential applications and benefits of PRP in medical practice. |
| format | Article |
| id | doaj-art-f5cfebcacdeb42eaa92901b084f33899 |
| institution | Kabale University |
| issn | 2589-0042 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj-art-f5cfebcacdeb42eaa92901b084f338992025-01-18T05:05:04ZengElsevieriScience2589-00422025-02-01282111705The role of platelet-rich plasma in biomedicine: A comprehensive overviewZhixin Zhang0Peng Liu1Xinmiao Xue2Zhiyu Zhang3Li Wang4Yvke Jiang5Chi Zhang6Hanwen Zhou7Shuhan Lv8Weidong Shen9Shiming Yang10Fangyuan Wang11Senior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, ChinaSchool of Physics and Optoelectronic Engineering Xidian University, Xi’an 710071, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, ChinaSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Graduate School of Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; Corresponding authorSenior Department of Otolaryngology Head and Neck Surgery, the Sixth Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing 100853, China; State Key Laboratory of Hearing and Balance Science, Beijing 100853, China; National Clinical Research Center for Otolaryngologic Diseases, Beijing 100853, China; Key Laboratory of Hearing Science, Ministry of Education, Beijing 100853, China; Beijing Key Laboratory of Hearing Impairment Prevention and Treatment, Beijing 100853, China; Corresponding authorSummary: Biomedicine has seen significant advancements in the 21st century, with platelet-rich plasma (PRP) playing a crucial role in clinical practice. This blood derivative, enriched with platelet components, has shown great potential for promoting tissue repair and regeneration. Its wide range of applications and the presence of anti-inflammatory and growth-promoting factors make it a valuable tool in the field of biomedicine. The exploration of PRP in clinical settings has been gaining momentum. Despite its cost-effectiveness, safety, and therapeutic efficacy, the widespread clinical adoption of PRP has been hindered by the absence of consistent preparation standards and standardized treatment protocols. This article provides a comprehensive analysis of the clinical uses, physiological roles, molecular mechanisms, and preparation techniques of PRP in biomedicine. The aim is to offer a thorough understanding of the potential applications and benefits of PRP in medical practice.http://www.sciencedirect.com/science/article/pii/S2589004224029328Health sciencesNatural sciencesApplied sciences |
| spellingShingle | Zhixin Zhang Peng Liu Xinmiao Xue Zhiyu Zhang Li Wang Yvke Jiang Chi Zhang Hanwen Zhou Shuhan Lv Weidong Shen Shiming Yang Fangyuan Wang The role of platelet-rich plasma in biomedicine: A comprehensive overview iScience Health sciences Natural sciences Applied sciences |
| title | The role of platelet-rich plasma in biomedicine: A comprehensive overview |
| title_full | The role of platelet-rich plasma in biomedicine: A comprehensive overview |
| title_fullStr | The role of platelet-rich plasma in biomedicine: A comprehensive overview |
| title_full_unstemmed | The role of platelet-rich plasma in biomedicine: A comprehensive overview |
| title_short | The role of platelet-rich plasma in biomedicine: A comprehensive overview |
| title_sort | role of platelet rich plasma in biomedicine a comprehensive overview |
| topic | Health sciences Natural sciences Applied sciences |
| url | http://www.sciencedirect.com/science/article/pii/S2589004224029328 |
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