Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the Literature

Massive splenic infarction (MSI) is a rare phenomenon that results from compromised blood flow to more than half of the spleen. Causes of MSI include hematological disorders, coagulopathies, infection, and embolization, and, rarely, MSI is spontaneous. The mainstay of treatment is splenectomy. We re...

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Main Authors: Christine L. Bokman, Maroun Sfeir, Veer Chahwala, Enrique Ginzburg
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2014/510259
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author Christine L. Bokman
Maroun Sfeir
Veer Chahwala
Enrique Ginzburg
author_facet Christine L. Bokman
Maroun Sfeir
Veer Chahwala
Enrique Ginzburg
author_sort Christine L. Bokman
collection DOAJ
description Massive splenic infarction (MSI) is a rare phenomenon that results from compromised blood flow to more than half of the spleen. Causes of MSI include hematological disorders, coagulopathies, infection, and embolization, and, rarely, MSI is spontaneous. The mainstay of treatment is splenectomy. We report the case of a 50-year-old man with a history of renal transplant who presented with diffuse abdominal pain and rapidly developed septic shock. A computed tomographic study (CT scan) of the abdomen demonstrated MSI. The surgical team was consulted for splenectomy but conservative management was maintained and immune function preserved. The patient’s clinical condition was resolved over a three-week period. This report demonstrates successful nonoperative management of a spontaneous MSI most likely secondary to hypoperfusion and a hypercoagulable state from both septic shock and renal transplant.
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spelling doaj-art-f5cfb0b8783f44bb91f748670e375e472025-02-03T05:58:20ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/510259510259Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the LiteratureChristine L. Bokman0Maroun Sfeir1Veer Chahwala2Enrique Ginzburg3DeWitt-Daughtry Family, Department of Surgery, University of Miami Miller School of Medicine and Ryder Trauma Center/Jackson Memorial Hospital, Miami, FL 33136, USADepartment of Internal Medicine, University of Miami Miller School of Medicine and Jackson Memorial Hospital, Miami, FL 33136, USADeWitt-Daughtry Family, Department of Surgery, University of Miami Miller School of Medicine and Ryder Trauma Center/Jackson Memorial Hospital, Miami, FL 33136, USADeWitt-Daughtry Family, Department of Surgery, University of Miami Miller School of Medicine and Ryder Trauma Center/Jackson Memorial Hospital, Miami, FL 33136, USAMassive splenic infarction (MSI) is a rare phenomenon that results from compromised blood flow to more than half of the spleen. Causes of MSI include hematological disorders, coagulopathies, infection, and embolization, and, rarely, MSI is spontaneous. The mainstay of treatment is splenectomy. We report the case of a 50-year-old man with a history of renal transplant who presented with diffuse abdominal pain and rapidly developed septic shock. A computed tomographic study (CT scan) of the abdomen demonstrated MSI. The surgical team was consulted for splenectomy but conservative management was maintained and immune function preserved. The patient’s clinical condition was resolved over a three-week period. This report demonstrates successful nonoperative management of a spontaneous MSI most likely secondary to hypoperfusion and a hypercoagulable state from both septic shock and renal transplant.http://dx.doi.org/10.1155/2014/510259
spellingShingle Christine L. Bokman
Maroun Sfeir
Veer Chahwala
Enrique Ginzburg
Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the Literature
Case Reports in Medicine
title Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the Literature
title_full Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the Literature
title_fullStr Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the Literature
title_full_unstemmed Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the Literature
title_short Spontaneous Massive Splenic Infarction in the Setting of Renal Transplant and Septic Shock: A Case Report and Review of the Literature
title_sort spontaneous massive splenic infarction in the setting of renal transplant and septic shock a case report and review of the literature
url http://dx.doi.org/10.1155/2014/510259
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