WNT inhibitor SP5-mediated SERPING1 suppresses lung adenocarcinoma progression via TSC2/mTOR pathway
Abstract The long-term outlook for patients grappling with lung cancer (LC) remains bleak, with lung adenocarcinoma (LUAD) emerging as the most predominant histological subtype. Our Mendelian randomization (MR) investigation spotlighted that heightened levels of the circulating protein serpin peptid...
Saved in:
| Main Authors: | Yefeng Shen, Xiaofeng Dong, Xujia Li, Zhiyuan Shi, Tingting Shao, Junlan Jiang, Jian Song |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-02-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07440-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
TSC complex decrease the expression of mTOR by regulated miR-199b-3p
by: Na Zhao, et al.
Published: (2025-01-01) -
Publisher Correction: TSC complex decrease the expression of mTOR by regulated miR-199b-3p
by: Na Zhao, et al.
Published: (2025-06-01) -
TSC2-mutated perivascular epithelioid cell tumor with partial response to mTOR inhibition: a case report and literature review
by: Xiaopeng Suo, et al.
Published: (2025-07-01) -
Genetic Evidence Supporting the Repurposing of mTOR Inhibitors for Reducing BMI
by: Ping Peng, et al.
Published: (2025-03-01) -
SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways
by: Lipeng Wu, et al.
Published: (2025-02-01)