Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection.

Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection.

Ebola virus (EBOV) causes a severe hemorrhagic disease with high fatality. Virus-like particles (VLPs) are a promising vaccine candidate against EBOV. We recently showed that VLPs protect mice from lethal EBOV infection when given before or after viral infection. To elucidate pathways through which...

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Bibliographic Details
Main Authors: Natarajan Ayithan, Steven B Bradfute, Scott M Anthony, Kelly S Stuthman, Sina Bavari, Mike Bray, Keiko Ozato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118345&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118345&type=printable

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