Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis

Invasive group A Streptococcus infections are associated with diverse presentations. We report a severe, rare case of GAS infection with dissemination including endocarditis and STSS. While whole genome sequencing of blood and pharyngeal isolates did not reveal any unique features attributable to th...

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Main Authors: Morouge Alramadhan, Gloria P. Heresi, Anthony R. Flores
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2019/6568732
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author Morouge Alramadhan
Gloria P. Heresi
Anthony R. Flores
author_facet Morouge Alramadhan
Gloria P. Heresi
Anthony R. Flores
author_sort Morouge Alramadhan
collection DOAJ
description Invasive group A Streptococcus infections are associated with diverse presentations. We report a severe, rare case of GAS infection with dissemination including endocarditis and STSS. While whole genome sequencing of blood and pharyngeal isolates did not reveal any unique features attributable to the severe presentation, our approach serves as a template for investigation of severe manifestations of common infections.
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id doaj-art-f538da0ae5e147beb29f2d5cbecd4351
institution Kabale University
issn 2090-6625
2090-6633
language English
publishDate 2019-01-01
publisher Wiley
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series Case Reports in Infectious Diseases
spelling doaj-art-f538da0ae5e147beb29f2d5cbecd43512025-02-03T06:00:38ZengWileyCase Reports in Infectious Diseases2090-66252090-66332019-01-01201910.1155/2019/65687326568732Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and EndocarditisMorouge Alramadhan0Gloria P. Heresi1Anthony R. Flores2Division of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, USADivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, USADivision of Infectious Diseases, Department of Pediatrics, McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, USAInvasive group A Streptococcus infections are associated with diverse presentations. We report a severe, rare case of GAS infection with dissemination including endocarditis and STSS. While whole genome sequencing of blood and pharyngeal isolates did not reveal any unique features attributable to the severe presentation, our approach serves as a template for investigation of severe manifestations of common infections.http://dx.doi.org/10.1155/2019/6568732
spellingShingle Morouge Alramadhan
Gloria P. Heresi
Anthony R. Flores
Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis
Case Reports in Infectious Diseases
title Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis
title_full Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis
title_fullStr Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis
title_full_unstemmed Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis
title_short Severe emm89 Group A Streptococcal Disease Characterized by Toxic Shock and Endocarditis
title_sort severe emm89 group a streptococcal disease characterized by toxic shock and endocarditis
url http://dx.doi.org/10.1155/2019/6568732
work_keys_str_mv AT morougealramadhan severeemm89groupastreptococcaldiseasecharacterizedbytoxicshockandendocarditis
AT gloriapheresi severeemm89groupastreptococcaldiseasecharacterizedbytoxicshockandendocarditis
AT anthonyrflores severeemm89groupastreptococcaldiseasecharacterizedbytoxicshockandendocarditis