Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress
The study was conducted with the primary objective to establish the influence of melatonin on adrenocortical functions to ameliorate thermal stress in goats. Endocrine secretions and several other blood biochemical parameters reflecting the animals adrenocortical stress response were determined over...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Veterinary Medicine International |
| Online Access: | http://dx.doi.org/10.4061/2010/348919 |
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| author | Veerasamy Sejian Rajendra Swaroop Srivastava |
| author_facet | Veerasamy Sejian Rajendra Swaroop Srivastava |
| author_sort | Veerasamy Sejian |
| collection | DOAJ |
| description | The study was conducted with the primary objective to establish the influence of melatonin on adrenocortical functions to ameliorate thermal stress in goats. Endocrine secretions and several other blood biochemical parameters reflecting the animals adrenocortical stress response were determined over a one-week period after goats had been exposed to 40C∘ and 60%RH for 10 days. The study was conducted for a period of 17 days in psychrometric chamber. The animals served as self-controls prior to start of the experiment. Blood samples were drawn on day 10 to establish effect of thermal stress. Chemical adrenalectomy was achieved using metyrapone followed by exogenous melatonin treatment. 40C∘ of thermal stress which is quite normal in tropical zone significantly (P≤.05) influenced all parameters except plasma insulin. Metyrapone treatment significantly (P≤.05) affected plasma levels of glucose, total protein, total cholesterol, cortisol, and aldosterone. Metyrapone aggravated thermal stress by decreasing cortisol level in goats. Melatonin treatment at 11:00 AM significantly (P≤.05) influenced plasma levels of glucose, total protein, total cholesterol, cortisol, aldosterone and insulin. Metyrapone treatment aggravated thermal stress although administration of melatonin could ameliorate the condition. This establishes the role of melatonin in relieving thermal stress in goats. |
| format | Article |
| id | doaj-art-f532a14677fd4deca783401e37ba377d |
| institution | Kabale University |
| issn | 2042-0048 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine International |
| spelling | doaj-art-f532a14677fd4deca783401e37ba377d2025-02-03T06:11:07ZengWileyVeterinary Medicine International2042-00482010-01-01201010.4061/2010/348919348919Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal StressVeerasamy Sejian0Rajendra Swaroop Srivastava1Neurophysiology Laboratory, Division of Physiology and Climatology, Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, IndiaNeurophysiology Laboratory, Division of Physiology and Climatology, Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, IndiaThe study was conducted with the primary objective to establish the influence of melatonin on adrenocortical functions to ameliorate thermal stress in goats. Endocrine secretions and several other blood biochemical parameters reflecting the animals adrenocortical stress response were determined over a one-week period after goats had been exposed to 40C∘ and 60%RH for 10 days. The study was conducted for a period of 17 days in psychrometric chamber. The animals served as self-controls prior to start of the experiment. Blood samples were drawn on day 10 to establish effect of thermal stress. Chemical adrenalectomy was achieved using metyrapone followed by exogenous melatonin treatment. 40C∘ of thermal stress which is quite normal in tropical zone significantly (P≤.05) influenced all parameters except plasma insulin. Metyrapone treatment significantly (P≤.05) affected plasma levels of glucose, total protein, total cholesterol, cortisol, and aldosterone. Metyrapone aggravated thermal stress by decreasing cortisol level in goats. Melatonin treatment at 11:00 AM significantly (P≤.05) influenced plasma levels of glucose, total protein, total cholesterol, cortisol, aldosterone and insulin. Metyrapone treatment aggravated thermal stress although administration of melatonin could ameliorate the condition. This establishes the role of melatonin in relieving thermal stress in goats.http://dx.doi.org/10.4061/2010/348919 |
| spellingShingle | Veerasamy Sejian Rajendra Swaroop Srivastava Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress Veterinary Medicine International |
| title | Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress |
| title_full | Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress |
| title_fullStr | Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress |
| title_full_unstemmed | Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress |
| title_short | Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress |
| title_sort | effects of melatonin on adrenal cortical functions of indian goats under thermal stress |
| url | http://dx.doi.org/10.4061/2010/348919 |
| work_keys_str_mv | AT veerasamysejian effectsofmelatoninonadrenalcorticalfunctionsofindiangoatsunderthermalstress AT rajendraswaroopsrivastava effectsofmelatoninonadrenalcorticalfunctionsofindiangoatsunderthermalstress |