Direct Vasocontractile Activities of Bupivacaine Enantiomers on the Isolated Rat Thoracic Aorta

Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(−)- and R(+)-bupivacaine. Methods. We performed functional examinations using isolated intact tho...

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Bibliographic Details
Main Authors: Mai Mukozawa, Ko Takakura, Maki Mizogami
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Anesthesiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/820186
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