DRG2 as a Biomarker to Enhance the Predictive Efficacy of PD-L1 Immunohistochemistry Assays

DRG2 as a Biomarker to Enhance the Predictive Efficacy of PD-L1 Immunohistochemistry Assays

PD-L1 immunohistochemistry (IHC) assays are used as a companion diagnostic for immunotherapy with immune checkpoint inhibitors (ICIs). However, despite the association between PD-L1 expression and clinical benefit from ICIs, the PD-L1 IHC assay is not sufficiently accurate in predicting response to...

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Bibliographic Details
Main Authors: Muralidharan Mani, Seong Hee Choi, Hyuk Nam Kwon, Jeong Woo Park
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
DRG2
PD-L1
endosomal trafficking
ICI
predictive efficacy
Online Access:https://www.mdpi.com/2227-9059/13/1/56
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