Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole
Aim. This study aims to evaluate the morphology of ganglion cell complex (GCC) along with functional outcomes in patients undergoing vitrectomy with ILM peeling and macular abrasion with Tano diamond dusted membrane scrapers (DDMS) for three different stages of the idiopathic macular hole (IMH). Met...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/8891057 |
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| author | Aurelio Imburgia Purva Date Alessandro Mularoni Gian Maria Cavallini Rodolfo Mastropasqua Matteo Forlini |
| author_facet | Aurelio Imburgia Purva Date Alessandro Mularoni Gian Maria Cavallini Rodolfo Mastropasqua Matteo Forlini |
| author_sort | Aurelio Imburgia |
| collection | DOAJ |
| description | Aim. This study aims to evaluate the morphology of ganglion cell complex (GCC) along with functional outcomes in patients undergoing vitrectomy with ILM peeling and macular abrasion with Tano diamond dusted membrane scrapers (DDMS) for three different stages of the idiopathic macular hole (IMH). Methods. This retrospective study was conducted between April 2019 and December 2019. 33 patients with IMH were included and divided into three groups: stage I, stage II, and stage IV. All patients were subjected to vitrectomy with ILM peeling. Gentle and vigorous macular abrasion was additionally performed for stage II and stage IV patients, respectively. The best-corrected visual acuity (BCVA), GCC thickness (measured by spectral domain-optical coherence tomography (SD-OCT)), and photopic contrast sensitivity (Rodenstock CV 900 Chart Panel) were determined before surgery and at 1- and 3-month follow-ups. Results. Closure of MH was achieved in all the patients. The difference between the preoperative and one- and three-month postoperative values of BCVA was statistically significant in the three groups (P<0.01). Contrast sensitivity progressively improved in all patients and was statistically significant (P<0.01). The reduction in GCC thickness during follow-up was 34%–42% of the preoperative measurements. On comparing the mean GCC thickness of the operated and healthy eyes, it was not statistically significant in stage I patients. However, the same when done in stage II and IV was statistically significant with P value < 0.05 and P<0.01, respectively. Conclusion. Combining ILM peeling with macular abrasion in advanced stages of MH may facilitate its closure without significantly affecting the functional outcome. |
| format | Article |
| id | doaj-art-f50ce6f0b51244d0b237fc2e6375f1b6 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-f50ce6f0b51244d0b237fc2e6375f1b62025-02-03T06:00:48ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/88910578891057Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular HoleAurelio Imburgia0Purva Date1Alessandro Mularoni2Gian Maria Cavallini3Rodolfo Mastropasqua4Matteo Forlini5Department of Ophthalmology, San Marino State Hospital, Cailungo, San MarinoValvekar Medical & Research Centre, Solapur, IndiaDepartment of Ophthalmology, San Marino State Hospital, Cailungo, San MarinoInstitute of Ophthalmology, University of Modena, Modena, ItalyInstitute of Ophthalmology, University of Modena, Modena, ItalyDepartment of Ophthalmology, San Marino State Hospital, Cailungo, San MarinoAim. This study aims to evaluate the morphology of ganglion cell complex (GCC) along with functional outcomes in patients undergoing vitrectomy with ILM peeling and macular abrasion with Tano diamond dusted membrane scrapers (DDMS) for three different stages of the idiopathic macular hole (IMH). Methods. This retrospective study was conducted between April 2019 and December 2019. 33 patients with IMH were included and divided into three groups: stage I, stage II, and stage IV. All patients were subjected to vitrectomy with ILM peeling. Gentle and vigorous macular abrasion was additionally performed for stage II and stage IV patients, respectively. The best-corrected visual acuity (BCVA), GCC thickness (measured by spectral domain-optical coherence tomography (SD-OCT)), and photopic contrast sensitivity (Rodenstock CV 900 Chart Panel) were determined before surgery and at 1- and 3-month follow-ups. Results. Closure of MH was achieved in all the patients. The difference between the preoperative and one- and three-month postoperative values of BCVA was statistically significant in the three groups (P<0.01). Contrast sensitivity progressively improved in all patients and was statistically significant (P<0.01). The reduction in GCC thickness during follow-up was 34%–42% of the preoperative measurements. On comparing the mean GCC thickness of the operated and healthy eyes, it was not statistically significant in stage I patients. However, the same when done in stage II and IV was statistically significant with P value < 0.05 and P<0.01, respectively. Conclusion. Combining ILM peeling with macular abrasion in advanced stages of MH may facilitate its closure without significantly affecting the functional outcome.http://dx.doi.org/10.1155/2020/8891057 |
| spellingShingle | Aurelio Imburgia Purva Date Alessandro Mularoni Gian Maria Cavallini Rodolfo Mastropasqua Matteo Forlini Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole Journal of Ophthalmology |
| title | Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole |
| title_full | Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole |
| title_fullStr | Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole |
| title_full_unstemmed | Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole |
| title_short | Evaluation of the Morphology of Ganglion Cell Complex and Functional Outcomes after Internal Limiting Membrane Peeling with Macular Abrasion in Idiopathic Macular Hole |
| title_sort | evaluation of the morphology of ganglion cell complex and functional outcomes after internal limiting membrane peeling with macular abrasion in idiopathic macular hole |
| url | http://dx.doi.org/10.1155/2020/8891057 |
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