Glucose variability and mode of anaesthesia in major noncardiac surgery (GlucoVITAL): study protocol for a randomised controlled trial

Glucose variability and mode of anaesthesia in major noncardiac surgery (GlucoVITAL): study protocol for a randomised controlled trial

Background: Hyperglycaemia after noncardiac surgery occurs commonly and is associated with complications. The choice of maintenance anaesthesia may promote hyperglycaemia and increase glucose variability, both of which exacerbate inflammation and organ dysfunction. We hypothesise that total intraven...

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Main Authors: Henrike Janssen, Priyanthi Dias, Louise Hiller, Russell Hewson, Rupert M. Pearse, Nick S. Oliver, Shaman Jhanji, Gareth L. Ackland, Ashok Sundar, Islam Abousharkh, Jai Varale, Joyce Yeung, Rupert Pearse, Benjamin Shelley, Kamran Khan, Peter Jacob, James Noblet, Monica Jefford, Toby Reynolds, Ana Gutierrez del Arroyo, Abeer Samman, Saja Alharbi, Sanjali Ahuja, Helen T. Neo Phatsimo, Keagan Lewis Witts, Muhammad Abdullah Pirwani, Su Yen Lee, Madhura Sivakumar, Divyani Priyavadan Bhudia, Marina Lily Chan, Emmanuella Anobah Adu, Marta Korbonits, Sian Henson, Onika Ottley, Mareena Joseph, Augustine Miguel Saavedra, Ana Santos, Eleanor Reeves, Joanne Gresty, Celinamma Maliaykal, Karthik Iyer, Lesley Horton, Helen Taylor, Ashok Nair, Catriona Frankling, Chloe Uffendell, Caroline Thomas, Catherine Moriarty, Beverley Jackson, Daniel Ruane, Reyhaneh Sadegh Zadeh, Ethel Black, Karmina Claros, Nick Perry, Vasiliki Manou-Stathopoulou, Ravishankar Rao Baikady, Holly Townsend-Thorn, Nicole Whitehead, Kate Tatham, Sophie Uren, Richard Gordon-Williams, Don Milliken, Jaishel Patel, Maxime Cordon-Goudreau, Edward Watson, Tom Craig, Francesca Mazzola, Richard Snooks, Sameer Ganatra
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:BJA Open
Subjects:
continuous glucose monitoring
glucose
infections
myocardial injury
postoperative complications
Online Access:http://www.sciencedirect.com/science/article/pii/S2772609625000437
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