Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression

Background. In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. Case Presentation. A 48-year-old...

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Main Authors: Daniel York, Pavan Patel, Smera Saikumar
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2022/3109331
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author Daniel York
Pavan Patel
Smera Saikumar
author_facet Daniel York
Pavan Patel
Smera Saikumar
author_sort Daniel York
collection DOAJ
description Background. In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. Case Presentation. A 48-year-old patient presented with a large fungating mass near her right inferior vulva with a hardness of surrounding tissues. The mass was 4 cm×3 cm in size and was excised in the operating room. The pathology was negative for malignancy; however, it showed lymphoplasmacytic proliferation with immunostaining positive for HSV virus. Conclusion. Atypical HSV pseudotumors should be considered in the differential diagnosis for an immunosuppressed patient who presents with a genital mass lesion.
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-f4f5ecbf1b1e432d9de4b9b81bed50442025-02-03T01:32:31ZengWileyCase Reports in Obstetrics and Gynecology2090-66922022-01-01202210.1155/2022/3109331Herpes Virus Pseudotumor in a Patient with HIV ImmunosuppressionDaniel York0Pavan Patel1Smera Saikumar2Colquitt Regional Medical CenterPhiladelphia College of Osteopathic MedicinePhiladelphia College of Osteopathic MedicineBackground. In rare cases, HSV infections can present as pseudotumors that are often mistaken as malignancies in patients with an uncontrolled HIV infection. Herpes simplex virus type 2 (HSV-2) infection rates range from 60% to 90% in individuals coinfected with HIV. Case Presentation. A 48-year-old patient presented with a large fungating mass near her right inferior vulva with a hardness of surrounding tissues. The mass was 4 cm×3 cm in size and was excised in the operating room. The pathology was negative for malignancy; however, it showed lymphoplasmacytic proliferation with immunostaining positive for HSV virus. Conclusion. Atypical HSV pseudotumors should be considered in the differential diagnosis for an immunosuppressed patient who presents with a genital mass lesion.http://dx.doi.org/10.1155/2022/3109331
spellingShingle Daniel York
Pavan Patel
Smera Saikumar
Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression
Case Reports in Obstetrics and Gynecology
title Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression
title_full Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression
title_fullStr Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression
title_full_unstemmed Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression
title_short Herpes Virus Pseudotumor in a Patient with HIV Immunosuppression
title_sort herpes virus pseudotumor in a patient with hiv immunosuppression
url http://dx.doi.org/10.1155/2022/3109331
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AT smerasaikumar herpesviruspseudotumorinapatientwithhivimmunosuppression