Prosigna Risk of Recurrence score and intrinsic subtypes are associated with adjuvant anthracycline chemotherapy benefit in high-risk breast cancer

Abstract NCIC-CTG MA.5 and DBCG 89D are symmetrically designed randomized trials comparing adjuvant cyclophosphamide, epirubicin, and fluorouracil with cyclophosphamide, methotrexate, and fluorouracil in high-risk breast cancer patients. In a joint analysis we evaluate the predictive value in terms...

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Bibliographic Details
Main Authors: Maj-Britt Jensen, Torsten O. Nielsen, John Bartlett, Anne-Vibeke Lænkholm, Lois Shepherd, Bent Ejlertsen
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-025-00738-7
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