Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery

Retinoblastoma is one of the most common ophthalmic neoplasms affecting children worldwide. Since its recent introduction, superselective ophthalmic artery injection of chemotherapy with melphalan has significantly reduced the need for enucleation in patients with advanced disease and also shown to...

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Main Authors: Stephan Klumpp, Lydia M. Jorge, Mohammed Ali Aziz-Sultan
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2013/408670
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author Stephan Klumpp
Lydia M. Jorge
Mohammed Ali Aziz-Sultan
author_facet Stephan Klumpp
Lydia M. Jorge
Mohammed Ali Aziz-Sultan
author_sort Stephan Klumpp
collection DOAJ
description Retinoblastoma is one of the most common ophthalmic neoplasms affecting children worldwide. Since its recent introduction, superselective ophthalmic artery injection of chemotherapy with melphalan has significantly reduced the need for enucleation in patients with advanced disease and also shown to have minimal adverse effects on visual acuity as compared to the conventional therapy. Although no severe complications resulting in strokes or deaths have been reported, this treatment modality is not without difficulties. In this case discussion, we describe an event that has occurred to several pediatric patients undergoing superselective angiography of the ophthalmic artery that may be due to an oculopulmonary type reflex causing significant hemodynamic instability and hypoxemia.
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series Case Reports in Anesthesiology
spelling doaj-art-f48cfdad6f144a4092ded0b0d438927c2025-02-03T05:57:09ZengWileyCase Reports in Anesthesiology2090-63822090-63902013-01-01201310.1155/2013/408670408670Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic ArteryStephan Klumpp0Lydia M. Jorge1Mohammed Ali Aziz-Sultan2Department of Clinical Anesthesia, Jackson Memorial Hospital, University of Miami, Miami, FL 33136, USADepartment of Clinical Anesthesia, Jackson Memorial Hospital, University of Miami, Miami, FL 33136, USADepartment of Clinical Neurologic Surgery, 201 Pope Life Center, University of Miami, Miami, FL 33136, USARetinoblastoma is one of the most common ophthalmic neoplasms affecting children worldwide. Since its recent introduction, superselective ophthalmic artery injection of chemotherapy with melphalan has significantly reduced the need for enucleation in patients with advanced disease and also shown to have minimal adverse effects on visual acuity as compared to the conventional therapy. Although no severe complications resulting in strokes or deaths have been reported, this treatment modality is not without difficulties. In this case discussion, we describe an event that has occurred to several pediatric patients undergoing superselective angiography of the ophthalmic artery that may be due to an oculopulmonary type reflex causing significant hemodynamic instability and hypoxemia.http://dx.doi.org/10.1155/2013/408670
spellingShingle Stephan Klumpp
Lydia M. Jorge
Mohammed Ali Aziz-Sultan
Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery
Case Reports in Anesthesiology
title Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery
title_full Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery
title_fullStr Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery
title_full_unstemmed Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery
title_short Hemodynamic Instability Induced by Superselective Angiography of the Ophthalmic Artery
title_sort hemodynamic instability induced by superselective angiography of the ophthalmic artery
url http://dx.doi.org/10.1155/2013/408670
work_keys_str_mv AT stephanklumpp hemodynamicinstabilityinducedbysuperselectiveangiographyoftheophthalmicartery
AT lydiamjorge hemodynamicinstabilityinducedbysuperselectiveangiographyoftheophthalmicartery
AT mohammedaliazizsultan hemodynamicinstabilityinducedbysuperselectiveangiographyoftheophthalmicartery