From memory impairment to two occluders in the heart – a multidisciplinary case report
Transient global amnesia (TGA) is a rare cause of a sudden onset of confusion and anterograde amnesia. It is considered of ischemic, epileptogenic, or venous origin. The etiology is uncertain, although hipertension, hiperlipidemia, and ischemic heart disease are considered as possible mechanisms. T...
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Language: | English |
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Vilnius University Press
2021-12-01
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Series: | Neurologijos seminarai |
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Online Access: | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27609 |
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author | A. Wiśniewski K. Filipska A. Ekkert |
author_facet | A. Wiśniewski K. Filipska A. Ekkert |
author_sort | A. Wiśniewski |
collection | DOAJ |
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Transient global amnesia (TGA) is a rare cause of a sudden onset of confusion and anterograde amnesia. It is considered of ischemic, epileptogenic, or venous origin. The etiology is uncertain, although hipertension, hiperlipidemia, and ischemic heart disease are considered as possible mechanisms. The impact of stress, migraine, physical effort is also highlighted. In contrast to ischemic stroke, atrial fibrillation (AF) and patent foramen ovale (PFO) are relatively rarely reported in the pathophysiology of acute memory impairment. In most cases, no visible lesion is detected on neuroimaging. This case report presents a 62-year-old woman with TGA symptoms who had an acute left temporal lobe ischemic lesion confirmed by diffusion-weighted imaging sequence of magnetic resonance imaging. Extensive workup revealed coexistence of AF and PFO. Due to intolerance to oral anticoagulants, percutaneous closure of left atrial appendage and PFO was performed within two months. Combined heart interventions have proven to be a safe and efficient therapeutic option for secondary stroke prevention in this patient. This case illustrates that patients with sudden memory impairment require careful observation and extensive workup, as well as a multidisciplinary approach and treatment.
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format | Article |
id | doaj-art-f48bb772e5ca496c84fcecb176122471 |
institution | Kabale University |
issn | 1392-3064 2424-5917 |
language | English |
publishDate | 2021-12-01 |
publisher | Vilnius University Press |
record_format | Article |
series | Neurologijos seminarai |
spelling | doaj-art-f48bb772e5ca496c84fcecb1761224712025-01-20T18:22:18ZengVilnius University PressNeurologijos seminarai1392-30642424-59172021-12-01254(90)10.29014/ns.2021.31From memory impairment to two occluders in the heart – a multidisciplinary case reportA. Wiśniewski 0K. Filipska 1A. Ekkert 2Nicolaus Copernicus University in Torun, PolandNicolaus Copernicus University in Torun, PolandVilnius University, Lithuania Transient global amnesia (TGA) is a rare cause of a sudden onset of confusion and anterograde amnesia. It is considered of ischemic, epileptogenic, or venous origin. The etiology is uncertain, although hipertension, hiperlipidemia, and ischemic heart disease are considered as possible mechanisms. The impact of stress, migraine, physical effort is also highlighted. In contrast to ischemic stroke, atrial fibrillation (AF) and patent foramen ovale (PFO) are relatively rarely reported in the pathophysiology of acute memory impairment. In most cases, no visible lesion is detected on neuroimaging. This case report presents a 62-year-old woman with TGA symptoms who had an acute left temporal lobe ischemic lesion confirmed by diffusion-weighted imaging sequence of magnetic resonance imaging. Extensive workup revealed coexistence of AF and PFO. Due to intolerance to oral anticoagulants, percutaneous closure of left atrial appendage and PFO was performed within two months. Combined heart interventions have proven to be a safe and efficient therapeutic option for secondary stroke prevention in this patient. This case illustrates that patients with sudden memory impairment require careful observation and extensive workup, as well as a multidisciplinary approach and treatment. https://www.journals.vu.lt/neurologijos_seminarai/article/view/27609transient global amnesiastrokepatent foramen ovaleatrial fibrillationpercutaneous occlusion |
spellingShingle | A. Wiśniewski K. Filipska A. Ekkert From memory impairment to two occluders in the heart – a multidisciplinary case report Neurologijos seminarai transient global amnesia stroke patent foramen ovale atrial fibrillation percutaneous occlusion |
title | From memory impairment to two occluders in the heart – a multidisciplinary case report |
title_full | From memory impairment to two occluders in the heart – a multidisciplinary case report |
title_fullStr | From memory impairment to two occluders in the heart – a multidisciplinary case report |
title_full_unstemmed | From memory impairment to two occluders in the heart – a multidisciplinary case report |
title_short | From memory impairment to two occluders in the heart – a multidisciplinary case report |
title_sort | from memory impairment to two occluders in the heart a multidisciplinary case report |
topic | transient global amnesia stroke patent foramen ovale atrial fibrillation percutaneous occlusion |
url | https://www.journals.vu.lt/neurologijos_seminarai/article/view/27609 |
work_keys_str_mv | AT awisniewski frommemoryimpairmenttotwooccludersintheheartamultidisciplinarycasereport AT kfilipska frommemoryimpairmenttotwooccludersintheheartamultidisciplinarycasereport AT aekkert frommemoryimpairmenttotwooccludersintheheartamultidisciplinarycasereport |