From memory impairment to two occluders in the heart – a multidisciplinary case report

Transient global amnesia (TGA) is a rare cause of a sudden onset of confusion and anterograde amnesia. It is considered of ischemic, epileptogenic, or venous origin. The etiology is uncertain, although hipertension, hiperlipidemia, and ischemic heart disease are considered as possible mechanisms. T...

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Main Authors: A. Wiśniewski, K. Filipska, A. Ekkert
Format: Article
Language:English
Published: Vilnius University Press 2021-12-01
Series:Neurologijos seminarai
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Online Access:https://www.journals.vu.lt/neurologijos_seminarai/article/view/27609
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author A. Wiśniewski
K. Filipska
A. Ekkert
author_facet A. Wiśniewski
K. Filipska
A. Ekkert
author_sort A. Wiśniewski
collection DOAJ
description Transient global amnesia (TGA) is a rare cause of a sudden onset of confusion and anterograde amnesia. It is considered of ischemic, epileptogenic, or venous origin. The etiology is uncertain, although hipertension, hiperlipidemia, and ischemic heart disease are considered as possible mechanisms. The impact of stress, migraine, physical effort is also highlighted. In contrast to ischemic stroke, atrial fibrillation (AF) and patent foramen ovale (PFO) are relatively rarely reported in the pathophysiology of acute memory impairment. In most cases, no visible lesion is detected on neuroimaging. This case report presents a 62-year-old woman with TGA symptoms who had an acute left temporal lobe ischemic lesion confirmed by diffusion-weighted imaging sequence of magnetic resonance imaging. Extensive workup revealed coexistence of AF and PFO. Due to intolerance to oral anticoagulants, percutaneous closure of left atrial appendage and PFO was performed within two months. Combined heart interventions have proven to be a safe and efficient therapeutic option for secondary stroke prevention in this patient. This case illustrates that patients with sudden memory impairment require careful observation and extensive workup, as well as a multidisciplinary approach and treatment.
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publisher Vilnius University Press
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series Neurologijos seminarai
spelling doaj-art-f48bb772e5ca496c84fcecb1761224712025-01-20T18:22:18ZengVilnius University PressNeurologijos seminarai1392-30642424-59172021-12-01254(90)10.29014/ns.2021.31From memory impairment to two occluders in the heart – a multidisciplinary case reportA. Wiśniewski 0K. Filipska 1A. Ekkert 2Nicolaus Copernicus University in Torun, PolandNicolaus Copernicus University in Torun, PolandVilnius University, Lithuania Transient global amnesia (TGA) is a rare cause of a sudden onset of confusion and anterograde amnesia. It is considered of ischemic, epileptogenic, or venous origin. The etiology is uncertain, although hipertension, hiperlipidemia, and ischemic heart disease are considered as possible mechanisms. The impact of stress, migraine, physical effort is also highlighted. In contrast to ischemic stroke, atrial fibrillation (AF) and patent foramen ovale (PFO) are relatively rarely reported in the pathophysiology of acute memory impairment. In most cases, no visible lesion is detected on neuroimaging. This case report presents a 62-year-old woman with TGA symptoms who had an acute left temporal lobe ischemic lesion confirmed by diffusion-weighted imaging sequence of magnetic resonance imaging. Extensive workup revealed coexistence of AF and PFO. Due to intolerance to oral anticoagulants, percutaneous closure of left atrial appendage and PFO was performed within two months. Combined heart interventions have proven to be a safe and efficient therapeutic option for secondary stroke prevention in this patient. This case illustrates that patients with sudden memory impairment require careful observation and extensive workup, as well as a multidisciplinary approach and treatment. https://www.journals.vu.lt/neurologijos_seminarai/article/view/27609transient global amnesiastrokepatent foramen ovaleatrial fibrillationpercutaneous occlusion
spellingShingle A. Wiśniewski
K. Filipska
A. Ekkert
From memory impairment to two occluders in the heart – a multidisciplinary case report
Neurologijos seminarai
transient global amnesia
stroke
patent foramen ovale
atrial fibrillation
percutaneous occlusion
title From memory impairment to two occluders in the heart – a multidisciplinary case report
title_full From memory impairment to two occluders in the heart – a multidisciplinary case report
title_fullStr From memory impairment to two occluders in the heart – a multidisciplinary case report
title_full_unstemmed From memory impairment to two occluders in the heart – a multidisciplinary case report
title_short From memory impairment to two occluders in the heart – a multidisciplinary case report
title_sort from memory impairment to two occluders in the heart a multidisciplinary case report
topic transient global amnesia
stroke
patent foramen ovale
atrial fibrillation
percutaneous occlusion
url https://www.journals.vu.lt/neurologijos_seminarai/article/view/27609
work_keys_str_mv AT awisniewski frommemoryimpairmenttotwooccludersintheheartamultidisciplinarycasereport
AT kfilipska frommemoryimpairmenttotwooccludersintheheartamultidisciplinarycasereport
AT aekkert frommemoryimpairmenttotwooccludersintheheartamultidisciplinarycasereport