Actin-dependent α-catenin oligomerization contributes to adherens junction assembly

Abstract Classic cadherins, specifically E-cadherin in most epithelial cells, are transmembrane adhesion receptors, whose intracellular region interacts with proteins, termed catenins, forming the cadherin-catenin complex (CCC). The cadherin ectodomain generates 2D adhesive clusters (E-clusters) thr...

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Bibliographic Details
Main Authors: Regina B. Troyanovsky, Indrajyoti Indra, Sergey M. Troyanovsky
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57079-z
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