An In vitro Caco2‐Based Model for Measuring Intestinal Bioadhesion Comparable to Ex vivo Models

This study presents an in vitro model using Caco‐2 cells that can mimic the bioadhesion properties of the human intestinal epithelium, aiming to reduce the use of animal tissues, in line with the 3Rs principle—replacement, reduction, and refinement. Specifically, a texture analyzer was used to asses...

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Bibliographic Details
Main Authors: Eliyahu Drori, Valeria Rahamim, Dhaval Patel, Yamm Anker, Sivan Meir, Gal Uzan, Shira Somech, Chen Drori, Tal Tzadok, Aharon Azagury
Format: Article
Language:English
Published: Wiley-VCH 2025-02-01
Series:Small Science
Subjects:
Online Access:https://doi.org/10.1002/smsc.202400461
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