An In vitro Caco2‐Based Model for Measuring Intestinal Bioadhesion Comparable to Ex vivo Models

An In vitro Caco2‐Based Model for Measuring Intestinal Bioadhesion Comparable to Ex vivo Models

This study presents an in vitro model using Caco‐2 cells that can mimic the bioadhesion properties of the human intestinal epithelium, aiming to reduce the use of animal tissues, in line with the 3Rs principle—replacement, reduction, and refinement. Specifically, a texture analyzer was used to asses...

Full description

Saved in:
Bibliographic Details
Main Authors: Eliyahu Drori, Valeria Rahamim, Dhaval Patel, Yamm Anker, Sivan Meir, Gal Uzan, Shira Somech, Chen Drori, Tal Tzadok, Aharon Azagury
Format: Article
Language:English
Published: Wiley-VCH 2025-02-01
Series:Small Science
Subjects:
alginate
bioadhesion
Caco‐2 cells
chitosan
ex vivo in vitro models
gelatin
Online Access:https://doi.org/10.1002/smsc.202400461
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items