Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for Tuberculosis

Tuberculosis (TB) remains to be the most prevalent and debilitating pulmonary (PTB) infection in the world today, affecting about one-third of the world's population. TB is an endemic disease in many developing countries, and efforts at eliminating the disease remain futile. While the course of...

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Main Authors: André P. Gabriel, Charles P. Mercado
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2011/984321
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author André P. Gabriel
Charles P. Mercado
author_facet André P. Gabriel
Charles P. Mercado
author_sort André P. Gabriel
collection DOAJ
description Tuberculosis (TB) remains to be the most prevalent and debilitating pulmonary (PTB) infection in the world today, affecting about one-third of the world's population. TB is an endemic disease in many developing countries, and efforts at eliminating the disease remain futile. While the course of the disease is indolent with years of latency, the reactivation of the disease can pose serious pulmonary and systemic infections that compromise multiple organ functions which lead to respiratory failure or end-organ damage. Despite attempts to control and eradicate the mycobacterium, the prevalence of the disease remains high due to increasing population rate, persistence of poverty and poor health care, treatment failure, increasing multidrug resistance as a consequence of treatment failure and poor compliance, and existence of comorbid conditions that compromise immune response. Limited government resources to screen and monitor disease progression of TB in third world countries hamper the eradication of the disease. In response, we have evaluated the efficiency and effectivity of a Community-Based Directly Observed Treatment, Short-Course (CB-DOTS), which is an equally effective alternative strategy to health center DOTS.
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spelling doaj-art-f450277dd0374fc78ed6d43d4ee23aa52025-02-03T01:03:15ZengWileyThe Scientific World Journal1537-744X2011-01-01112178218610.1100/2011/984321984321Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for TuberculosisAndré P. Gabriel0Charles P. Mercado1Department of Medicine, Columbia University Medical Center, New York, NY 10032, USADepartment of Medicine, Columbia University Medical Center, New York, NY 10032, USATuberculosis (TB) remains to be the most prevalent and debilitating pulmonary (PTB) infection in the world today, affecting about one-third of the world's population. TB is an endemic disease in many developing countries, and efforts at eliminating the disease remain futile. While the course of the disease is indolent with years of latency, the reactivation of the disease can pose serious pulmonary and systemic infections that compromise multiple organ functions which lead to respiratory failure or end-organ damage. Despite attempts to control and eradicate the mycobacterium, the prevalence of the disease remains high due to increasing population rate, persistence of poverty and poor health care, treatment failure, increasing multidrug resistance as a consequence of treatment failure and poor compliance, and existence of comorbid conditions that compromise immune response. Limited government resources to screen and monitor disease progression of TB in third world countries hamper the eradication of the disease. In response, we have evaluated the efficiency and effectivity of a Community-Based Directly Observed Treatment, Short-Course (CB-DOTS), which is an equally effective alternative strategy to health center DOTS.http://dx.doi.org/10.1100/2011/984321
spellingShingle André P. Gabriel
Charles P. Mercado
Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for Tuberculosis
The Scientific World Journal
title Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for Tuberculosis
title_full Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for Tuberculosis
title_fullStr Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for Tuberculosis
title_full_unstemmed Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for Tuberculosis
title_short Evaluation of Task Shifting in Community-Based DOTS Program as an Effective Control Strategy for Tuberculosis
title_sort evaluation of task shifting in community based dots program as an effective control strategy for tuberculosis
url http://dx.doi.org/10.1100/2011/984321
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