A male-female mathematical model of human papillomavirus (HPV) in African American population

We introduce mathematical human papillomavirus (HPV) epidemic models (with and without vaccination) for African American females (AAF) and African American males (AAM) with 'fitted' logistic demographics and use these models to study the HPV disease dynamics. The US Census Bureau data of A...

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Main Author: Najat Ziyadi
Format: Article
Language:English
Published: AIMS Press 2016-12-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2017022
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author Najat Ziyadi
author_facet Najat Ziyadi
author_sort Najat Ziyadi
collection DOAJ
description We introduce mathematical human papillomavirus (HPV) epidemic models (with and without vaccination) for African American females (AAF) and African American males (AAM) with 'fitted' logistic demographics and use these models to study the HPV disease dynamics. The US Census Bureau data of AAF and AAM of 16 years and older from 2000 to 2014 is used to 'fit' the logistic demographic models. We compute the basic reproduction number, $\mathcal{R}_0$ , and use it to show that $\mathcal{R}_0$ is less than 1 in the African American (AA) population with or without implementation of HPV vaccination program. Furthermore, we obtain that adopting a HPV vaccination policy in the AAF and AAM populations lower $\mathcal{R}_0$ and the number of HPV infections. Sensitivity analysis is used to illustrate the impact of each model parameter on the basic reproduction number.
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spelling doaj-art-f44326ca42cb4b768ddfdbfe803e8ec52025-01-24T02:39:32ZengAIMS PressMathematical Biosciences and Engineering1551-00182016-12-0114133935810.3934/mbe.2017022A male-female mathematical model of human papillomavirus (HPV) in African American populationNajat Ziyadi0Department of Mathematics, Morgan State University, Baltimore, MD 21251, USAWe introduce mathematical human papillomavirus (HPV) epidemic models (with and without vaccination) for African American females (AAF) and African American males (AAM) with 'fitted' logistic demographics and use these models to study the HPV disease dynamics. The US Census Bureau data of AAF and AAM of 16 years and older from 2000 to 2014 is used to 'fit' the logistic demographic models. We compute the basic reproduction number, $\mathcal{R}_0$ , and use it to show that $\mathcal{R}_0$ is less than 1 in the African American (AA) population with or without implementation of HPV vaccination program. Furthermore, we obtain that adopting a HPV vaccination policy in the AAF and AAM populations lower $\mathcal{R}_0$ and the number of HPV infections. Sensitivity analysis is used to illustrate the impact of each model parameter on the basic reproduction number.https://www.aimspress.com/article/doi/10.3934/mbe.2017022hpvlogistic demographicsbasic reproduction numbervaccine
spellingShingle Najat Ziyadi
A male-female mathematical model of human papillomavirus (HPV) in African American population
Mathematical Biosciences and Engineering
hpv
logistic demographics
basic reproduction number
vaccine
title A male-female mathematical model of human papillomavirus (HPV) in African American population
title_full A male-female mathematical model of human papillomavirus (HPV) in African American population
title_fullStr A male-female mathematical model of human papillomavirus (HPV) in African American population
title_full_unstemmed A male-female mathematical model of human papillomavirus (HPV) in African American population
title_short A male-female mathematical model of human papillomavirus (HPV) in African American population
title_sort male female mathematical model of human papillomavirus hpv in african american population
topic hpv
logistic demographics
basic reproduction number
vaccine
url https://www.aimspress.com/article/doi/10.3934/mbe.2017022
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