Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and Anxiety

Objectives. The study was aimed at providing a psychosocial profile for Iranian liver transplant candidates referred to an established liver transplantation program. Material and Methods. Patients assessed for liver transplant candidacy in Imam Khomeini Hospital (Tehran, Iran) between March 2013 and...

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Main Authors: Maryam Banihashemi, Mohsen Hafezi, Mohsen Nasiri-Toosi, Ali Jafarian, Mohammad Reza Abbasi, Mohammad Arbabi, Maryam Abdi, Mahzad Khavarian, Ali-Akbar Nejatisafa
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2015/329615
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author Maryam Banihashemi
Mohsen Hafezi
Mohsen Nasiri-Toosi
Ali Jafarian
Mohammad Reza Abbasi
Mohammad Arbabi
Maryam Abdi
Mahzad Khavarian
Ali-Akbar Nejatisafa
author_facet Maryam Banihashemi
Mohsen Hafezi
Mohsen Nasiri-Toosi
Ali Jafarian
Mohammad Reza Abbasi
Mohammad Arbabi
Maryam Abdi
Mahzad Khavarian
Ali-Akbar Nejatisafa
author_sort Maryam Banihashemi
collection DOAJ
description Objectives. The study was aimed at providing a psychosocial profile for Iranian liver transplant candidates referred to an established liver transplantation program. Material and Methods. Patients assessed for liver transplant candidacy in Imam Khomeini Hospital (Tehran, Iran) between March 2013 and September 2014 were included. The following battery of tests were administered: Psychosocial Assessment of Candidates for Transplant (PACT), the Short-Form health survey (SF-36), and Hospital Anxiety and Depression Scale (HADS). Results. Psychosocial assessment in 205 liver transplant candidates revealed significant impairments in several SF-36 domains; social functioning was the least and physical functioning was the most impaired domains. The prevalence of cases with probable anxiety and depressive disorders, according to HADS, was 13.8% and 5.6%, respectively. According to PACT, 24.3% of the assessed individuals were considered good or excellent candidates. In 11.2%, transplantation seemed poor candidate due to at least one major psychosocial or lifestyle risk factor. Poor candidate quality was associated with impaired health-related quality of life and higher scores on anxiety and depression scales (p<0.05). Conclusions. Transplant programs could implement specific intervention programs based on normative databases to address the psychosocial issues in patients in order to improve patient care, quality of life, and transplant outcomes.
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spelling doaj-art-f3f059fca1d24be3a1f1e795b64f8a9c2025-08-20T02:21:46ZengWileyJournal of Transplantation2090-00072090-00152015-01-01201510.1155/2015/329615329615Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and AnxietyMaryam Banihashemi0Mohsen Hafezi1Mohsen Nasiri-Toosi2Ali Jafarian3Mohammad Reza Abbasi4Mohammad Arbabi5Maryam Abdi6Mahzad Khavarian7Ali-Akbar Nejatisafa8Psychosomatic Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranPsychosomatic Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranNephrology Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranPsychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran 1333715914, IranPsychosomatic Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranPsychosomatic Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranLiver Transplantation Research Center, Tehran University of Medical Sciences, Tehran 1419733141, IranObjectives. The study was aimed at providing a psychosocial profile for Iranian liver transplant candidates referred to an established liver transplantation program. Material and Methods. Patients assessed for liver transplant candidacy in Imam Khomeini Hospital (Tehran, Iran) between March 2013 and September 2014 were included. The following battery of tests were administered: Psychosocial Assessment of Candidates for Transplant (PACT), the Short-Form health survey (SF-36), and Hospital Anxiety and Depression Scale (HADS). Results. Psychosocial assessment in 205 liver transplant candidates revealed significant impairments in several SF-36 domains; social functioning was the least and physical functioning was the most impaired domains. The prevalence of cases with probable anxiety and depressive disorders, according to HADS, was 13.8% and 5.6%, respectively. According to PACT, 24.3% of the assessed individuals were considered good or excellent candidates. In 11.2%, transplantation seemed poor candidate due to at least one major psychosocial or lifestyle risk factor. Poor candidate quality was associated with impaired health-related quality of life and higher scores on anxiety and depression scales (p<0.05). Conclusions. Transplant programs could implement specific intervention programs based on normative databases to address the psychosocial issues in patients in order to improve patient care, quality of life, and transplant outcomes.http://dx.doi.org/10.1155/2015/329615
spellingShingle Maryam Banihashemi
Mohsen Hafezi
Mohsen Nasiri-Toosi
Ali Jafarian
Mohammad Reza Abbasi
Mohammad Arbabi
Maryam Abdi
Mahzad Khavarian
Ali-Akbar Nejatisafa
Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and Anxiety
Journal of Transplantation
title Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and Anxiety
title_full Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and Anxiety
title_fullStr Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and Anxiety
title_full_unstemmed Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and Anxiety
title_short Psychosocial Status of Liver Transplant Candidates in Iran and Its Correlation with Health-Related Quality of Life and Depression and Anxiety
title_sort psychosocial status of liver transplant candidates in iran and its correlation with health related quality of life and depression and anxiety
url http://dx.doi.org/10.1155/2015/329615
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