Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids
Introduction: This study investigated the relationship between plasma amino acid levels and the presence of Helicobacter pylori (H. pylori) in children. Materials and Methods: The study included 88 pediatric patients with gastritis (30 H. pylori-positive and 58 H. pylori-negative) and a control gro...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2025-08-01
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| Series: | Güncel Pediatri |
| Subjects: | |
| Online Access: | https://www.guncelpediatri.com/articles/relationship-between-helicobacter-pylori-gastritis-and-plasma-amino-acids/doi/jcp.2025.32767 |
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| Summary: | Introduction: This study investigated the relationship between plasma amino acid levels and the presence of Helicobacter pylori (H. pylori) in children.
Materials and Methods: The study included 88 pediatric patients with gastritis (30 H. pylori-positive and 58 H. pylori-negative) and a control group of 32 children. Plasma amino acid levels were assessed using liquid chromatography-tandem mass spectrometry, and dietary amino acid intake for all participants was estimated based on a three-day dietary questionnaire.
Results: Plasma glycine, alanine and histidine levels were significantly high in the H. pylori-negative group compared to the other groups (p<0.05). Plasma cysteine, homocysteine and hydroxylysine levels were significantly higher in the control group compared to both gastritis groups (p<0.05). Plasma asparagine, glutamine and histidine levels were found significantly lower in the H. pylori positive group than in the H. pylori negative group (p<0.05).
Conclusion: This study identified a moderate correlation between plasma levels of asparagine, glutamine, and histidine and the presence of H. pylori gastritis in children. |
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| ISSN: | 1308-6308 |