Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment
The involvement of the central nervous system in case of Wegener granulomatosis (WG) is infrequent and usually leads to cranial nerve abnormalities, cerebrovascular events, and seizures. Meningeal involvement is quite rare and usually is due to the spreading from adjacent disease in the skull base....
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/750391 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832565274779320320 |
|---|---|
| author | Federico Nicolosi Giovanni Nodari Giannantonio Spena Elena Roca Karol Migliorati Giacomo Esposito Roberto Stefini Marco Fontanella Pier Paolo Panciani |
| author_facet | Federico Nicolosi Giovanni Nodari Giannantonio Spena Elena Roca Karol Migliorati Giacomo Esposito Roberto Stefini Marco Fontanella Pier Paolo Panciani |
| author_sort | Federico Nicolosi |
| collection | DOAJ |
| description | The involvement of the central nervous system in case of Wegener granulomatosis (WG) is infrequent and usually leads to cranial nerve abnormalities, cerebrovascular events, and seizures. Meningeal involvement is quite rare and usually is due to the spreading from adjacent disease in the skull base. We described the case of a remote intraparenchymal Wegener’s granuloma in a 55-year-old man presenting with seizures and a history of severe generalized WG. The radiological findings were not useful for the diagnosis, and the pharmacological treatment was ineffective. The importance of a surgery in case of localized WG has been emphasized, in order to confirm the diagnosis and to avoid additional medicaments, like antiepileptic drugs, potentially harmful in immunosuppressed patients. |
| format | Article |
| id | doaj-art-f3ebbd30b4b348928e49c731e2963d70 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-f3ebbd30b4b348928e49c731e2963d702025-02-03T01:08:50ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/750391750391Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and TreatmentFederico Nicolosi0Giovanni Nodari1Giannantonio Spena2Elena Roca3Karol Migliorati4Giacomo Esposito5Roberto Stefini6Marco Fontanella7Pier Paolo Panciani8Division of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyDivision of Neurosurgery, Department of Neuroscience, University of Brescia, Brescia, ItalyThe involvement of the central nervous system in case of Wegener granulomatosis (WG) is infrequent and usually leads to cranial nerve abnormalities, cerebrovascular events, and seizures. Meningeal involvement is quite rare and usually is due to the spreading from adjacent disease in the skull base. We described the case of a remote intraparenchymal Wegener’s granuloma in a 55-year-old man presenting with seizures and a history of severe generalized WG. The radiological findings were not useful for the diagnosis, and the pharmacological treatment was ineffective. The importance of a surgery in case of localized WG has been emphasized, in order to confirm the diagnosis and to avoid additional medicaments, like antiepileptic drugs, potentially harmful in immunosuppressed patients.http://dx.doi.org/10.1155/2013/750391 |
| spellingShingle | Federico Nicolosi Giovanni Nodari Giannantonio Spena Elena Roca Karol Migliorati Giacomo Esposito Roberto Stefini Marco Fontanella Pier Paolo Panciani Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment Case Reports in Neurological Medicine |
| title | Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment |
| title_full | Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment |
| title_fullStr | Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment |
| title_full_unstemmed | Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment |
| title_short | Cerebral Wegener’s Granuloma: Surgery Mandatory for Diagnosis and Treatment |
| title_sort | cerebral wegener s granuloma surgery mandatory for diagnosis and treatment |
| url | http://dx.doi.org/10.1155/2013/750391 |
| work_keys_str_mv | AT federiconicolosi cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT giovanninodari cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT giannantoniospena cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT elenaroca cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT karolmigliorati cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT giacomoesposito cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT robertostefini cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT marcofontanella cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment AT pierpaolopanciani cerebralwegenersgranulomasurgerymandatoryfordiagnosisandtreatment |