Comparisons of adverse events associated with immune checkpoint inhibitors in the treatment of non-small cell lung cancer: a real-world disproportionality analysis based on the FDA adverse event reporting system

Comparisons of adverse events associated with immune checkpoint inhibitors in the treatment of non-small cell lung cancer: a real-world disproportionality analysis based on the FDA adverse event reporting system

Abstract Background Immune checkpoint inhibitor (ICI) therapy is increasingly used to treat non-small cell lung cancer (NSCLC). However, little attention has been given to the comparative analysis of adverse events (AEs) associated with different ICIs. Methods Disproportionality analysis and Bayesia...

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Bibliographic Details
Main Authors: Ruichen Gao, Wenjun Liang, Jintao Chen, Mingxia Yang, Xiaowei Yu, Xiaohua Wang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
FDA adverse event reporting system
Non-small cell lung cancer
Immune checkpoint inhibitor
Immune-related adverse event
Pharmacovigilance signal
Matrix of pairwise comparison
Online Access:https://doi.org/10.1186/s12885-025-13614-1
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