Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case Reports
BACKGROUND: Primary biliary cirrhosis (PBC) may be associated with pruritus and, when present, may be accentuated during pregnancy. Several therapeutic modalities have been used to control itching caused by cholestasis, with variable responses. Drug therapies are ill-advised, particularly in early p...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2008-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2008/969826 |
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| _version_ | 1832549832767569920 |
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| author | Alallam Alallam David Barth E Jenny Heathcote |
| author_facet | Alallam Alallam David Barth E Jenny Heathcote |
| author_sort | Alallam Alallam |
| collection | DOAJ |
| description | BACKGROUND: Primary biliary cirrhosis (PBC) may be associated with pruritus and, when present, may be accentuated during pregnancy. Several therapeutic modalities have been used to control itching caused by cholestasis, with variable responses. Drug therapies are ill-advised, particularly in early pregnancy. Plasmapheresis has been successful in controlling pruritus in patients with cholestasis. The use of plasmapheresis to alleviate severe life-threatening pruritus during pregnancy is reported in two patients with PBC. |
| format | Article |
| id | doaj-art-f3c160765dbe4d66aa24590a97b09dad |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-f3c160765dbe4d66aa24590a97b09dad2025-02-03T06:08:28ZengWileyCanadian Journal of Gastroenterology0835-79002008-01-0122550550710.1155/2008/969826Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case ReportsAlallam Alallam0David Barth1E Jenny Heathcote2Department of Medicine, University Health Network, University of Toronto, Ontario, CanadaDepartment of Medicine, University Health Network, University of Toronto, Ontario, CanadaDepartment of Medicine, University Health Network, University of Toronto, Ontario, CanadaBACKGROUND: Primary biliary cirrhosis (PBC) may be associated with pruritus and, when present, may be accentuated during pregnancy. Several therapeutic modalities have been used to control itching caused by cholestasis, with variable responses. Drug therapies are ill-advised, particularly in early pregnancy. Plasmapheresis has been successful in controlling pruritus in patients with cholestasis. The use of plasmapheresis to alleviate severe life-threatening pruritus during pregnancy is reported in two patients with PBC.http://dx.doi.org/10.1155/2008/969826 |
| spellingShingle | Alallam Alallam David Barth E Jenny Heathcote Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case Reports Canadian Journal of Gastroenterology |
| title | Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case Reports |
| title_full | Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case Reports |
| title_fullStr | Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case Reports |
| title_full_unstemmed | Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case Reports |
| title_short | Role of Plasmapheresis in the Treatment of Severe Pruritus in Pregnant Patients with Primary Biliary Cirrhosis: Case Reports |
| title_sort | role of plasmapheresis in the treatment of severe pruritus in pregnant patients with primary biliary cirrhosis case reports |
| url | http://dx.doi.org/10.1155/2008/969826 |
| work_keys_str_mv | AT alallamalallam roleofplasmapheresisinthetreatmentofseverepruritusinpregnantpatientswithprimarybiliarycirrhosiscasereports AT davidbarth roleofplasmapheresisinthetreatmentofseverepruritusinpregnantpatientswithprimarybiliarycirrhosiscasereports AT ejennyheathcote roleofplasmapheresisinthetreatmentofseverepruritusinpregnantpatientswithprimarybiliarycirrhosiscasereports |