Exploring the Use of Helminthophagous Fungi in the Control of Helminthoses in Horses: A Review

Equine farming faces growing challenges with helminthoses, aggravated by the indiscriminate use of anthelmintics without technical criteria. This practice favors resistance to these drugs, generates residues in animal products, compromises food safety and human health, and, when excreted in large qu...

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Main Authors: Tábata Alves do Carmo, Júlia dos Santos Fonseca, Fabio Ribeiro Braga, Adolfo Paz-Silva, Ricardo Velludo Gomes de Soutello, Jackson Victor de Araújo
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/6/864
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Summary:Equine farming faces growing challenges with helminthoses, aggravated by the indiscriminate use of anthelmintics without technical criteria. This practice favors resistance to these drugs, generates residues in animal products, compromises food safety and human health, and, when excreted in large quantities, negatively impacts environmental health by affecting invertebrates and fecal microorganisms. This highlights the importance of the One Health approach. A promising alternative is biological control with nematophagous or helminthophagous fungi such as <i>Duddingtonia flagrans</i>, <i>Pochonia chlamydosporia</i>, <i>Arthrobotrys oligospora</i>, <i>Monacrosporium thaumasium</i>, <i>Mucor circinelloides</i> and <i>Purpureocillium lilacinum</i>. Due to their different mechanisms of action, ovicidal and predatory fungi, when used together, can act in a complementary and synergistic way in the biological control of helminths, increasing their effectiveness in reducing parasitic infections. The use of these fungi through biosynthesized nanoparticles from fungal filtrates is also emerging as a new approach to nematode control. It can be administered through feed supplementation in commercial formulations. The aim of this review is to explore the use of helminthophagous fungi in the control of helminthiases in horses, highlighting their potential as a biological alternative. It also aims to understand how these fungi can contribute effectively and sustainably to parasite management in horses.
ISSN:2076-2615