Integrated multi-omics analysis reveals clinical significance of hepatocyte nuclear factor-1β in tumor immune microenvironment, immunotherapy and prognostic prediction for colon adenocarcinoma
Abstract Background Research has consistently highlighted the key role of hepatocyte nuclear factor 1β (HNF1B) in organ development and cancer, including its involvement in colon cancer via shifted-code mutations. However, the specific effects of HNF1B on cancer immunotherapy and the immune microenv...
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Main Authors: | Fushan Gao, Wenlin Gong, Haihua He, Zhen Zhang, Hongcai Yang, Fei Shao, Yibo Gao, Jie He |
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Format: | Article |
Language: | English |
Published: |
Springer
2024-12-01
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Series: | Cancer Immunology, Immunotherapy |
Subjects: | |
Online Access: | https://doi.org/10.1007/s00262-024-03870-8 |
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