The Mechanistic Target of Rapamycin Mediates <i>Clostridium perfringens</i>-Induced Chicken Necrotic Enteritis Attenuated by Secondary Bile Acid Deoxycholic Acid

The Mechanistic Target of Rapamycin Mediates <i>Clostridium perfringens</i>-Induced Chicken Necrotic Enteritis Attenuated by Secondary Bile Acid Deoxycholic Acid

<i>Clostridium perfringens</i> is a prevalent gut bacterial pathogen in humans and animals. This study investigated the role of the mechanistic targets of rapamycin (mTOR) and deoxycholic acid (DCA) on <i>C. perfringens</i> intestinal infection. Chickens were sequentially inf...

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Bibliographic Details
Main Authors: Mohit Bansal, Tahrir Alenezi, Ying Fu, Janashrit Shrestha, Ayidh Almansour, Hong Wang, Anamika Gupta, Rohana Liyanage, Xiaolun Sun
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Microorganisms
Subjects:
host immune response
bile acid
ileitis
immune cell infiltration
cell death
Online Access:https://www.mdpi.com/2076-2607/13/4/762
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