Why and how should we simulate platform trials? Learnings from EU-PEARL

Why and how should we simulate platform trials? Learnings from EU-PEARL

Abstract Background Platform trials are innovative clinical trials governed by a master protocol that allows for the evaluation of multiple investigational treatments that enter and leave the trial over time. Interest in platform trials has been steadily increasing over the last decade. Due to their...

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Main Authors: Elias Laurin Meyer, Tobias Mielke, Marta Bofill Roig, Michaela Maria Freitag, Peter Jacko, Pavla Krotka, Peter Mesenbrink, Tom Parke, Sonja Zehetmayer, Dario Zocholl, Franz König
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medical Research Methodology
Subjects:
Platform trials
Simulations
Software
Open-source
R
Online Access:https://doi.org/10.1186/s12874-024-02453-6
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https://doi.org/10.1186/s12874-024-02453-6

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