Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland

Introduction. The variability of the location of the parathyroid glands is directly related to the events that occur during embryonic development. The impact that an individual submits more than four parathyroid glands is close to 13%. However the presentation of a parathyroid adenoma in a supernume...

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Main Authors: Fernando Mendoza-Moreno, Ángel Rodriguez-Pascual, María Rocío Díez-Gago, Marina Pérez-González, Laura Jiménez‐Alvárez, Isabel Furtado-Lobo, Manuel Díez‐Alonso, Fernando Noguerales-Fraguas
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2018/6482546
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author Fernando Mendoza-Moreno
Ángel Rodriguez-Pascual
María Rocío Díez-Gago
Marina Pérez-González
Laura Jiménez‐Alvárez
Isabel Furtado-Lobo
Manuel Díez‐Alonso
Fernando Noguerales-Fraguas
author_facet Fernando Mendoza-Moreno
Ángel Rodriguez-Pascual
María Rocío Díez-Gago
Marina Pérez-González
Laura Jiménez‐Alvárez
Isabel Furtado-Lobo
Manuel Díez‐Alonso
Fernando Noguerales-Fraguas
author_sort Fernando Mendoza-Moreno
collection DOAJ
description Introduction. The variability of the location of the parathyroid glands is directly related to the events that occur during embryonic development. The impact that an individual submits more than four parathyroid glands is close to 13%. However the presentation of a parathyroid adenoma in a supernumerary gland is an uncommon event. Case report. A 30-year-old man diagnosed with primary hyperparathyroidism with matching findings on ultrasonography and scintigraphy for parathyroid adenoma localization lower left regarding the thyroid gland. A cervicotomy explorer showed four orthotopic parathyroid glands. The biopsy of the inferior left gland was normal. No signs of adenoma were seen in the biopsy. Following mobilization of the ipsilateral thyroid lobe, fifth parathyroid gland was found increased significantly in size than proceeded to remove, confirming the diagnosis of adenoma. After the excision, the levels of serum calcium and parathyroid hormone were normalized. Conclusions. The presentation of a parathyroid adenoma in a supernumerary gland is a challenge for the surgeon. The high sensitivity having different imaging techniques has been a key to locate preoperatively the pathological parathyroid gland. Analytical or clinical persistence of primary hyperparathyroidism after parathyroid surgery can occur if the location of the adenoma is a supernumerary or ectopic gland location.
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spelling doaj-art-f34997c1696c4512a708ea39d5f8901f2025-02-03T01:28:47ZengWileyCase Reports in Otolaryngology2090-67652090-67732018-01-01201810.1155/2018/64825466482546Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary GlandFernando Mendoza-Moreno0Ángel Rodriguez-Pascual1María Rocío Díez-Gago2Marina Pérez-González3Laura Jiménez‐Alvárez4Isabel Furtado-Lobo5Manuel Díez‐Alonso6Fernando Noguerales-Fraguas7Department of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainDepartment of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainDepartment of Emergency Medicine, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainDepartment of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainDepartment of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainDepartment of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainDepartment of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainDepartment of General and Digestive Surgery, Príncipe de Asturias Teaching Hospital, Alcalá de Henares, Madrid, SpainIntroduction. The variability of the location of the parathyroid glands is directly related to the events that occur during embryonic development. The impact that an individual submits more than four parathyroid glands is close to 13%. However the presentation of a parathyroid adenoma in a supernumerary gland is an uncommon event. Case report. A 30-year-old man diagnosed with primary hyperparathyroidism with matching findings on ultrasonography and scintigraphy for parathyroid adenoma localization lower left regarding the thyroid gland. A cervicotomy explorer showed four orthotopic parathyroid glands. The biopsy of the inferior left gland was normal. No signs of adenoma were seen in the biopsy. Following mobilization of the ipsilateral thyroid lobe, fifth parathyroid gland was found increased significantly in size than proceeded to remove, confirming the diagnosis of adenoma. After the excision, the levels of serum calcium and parathyroid hormone were normalized. Conclusions. The presentation of a parathyroid adenoma in a supernumerary gland is a challenge for the surgeon. The high sensitivity having different imaging techniques has been a key to locate preoperatively the pathological parathyroid gland. Analytical or clinical persistence of primary hyperparathyroidism after parathyroid surgery can occur if the location of the adenoma is a supernumerary or ectopic gland location.http://dx.doi.org/10.1155/2018/6482546
spellingShingle Fernando Mendoza-Moreno
Ángel Rodriguez-Pascual
María Rocío Díez-Gago
Marina Pérez-González
Laura Jiménez‐Alvárez
Isabel Furtado-Lobo
Manuel Díez‐Alonso
Fernando Noguerales-Fraguas
Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland
Case Reports in Otolaryngology
title Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland
title_full Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland
title_fullStr Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland
title_full_unstemmed Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland
title_short Primary Hyperparathyroidism due to Parathyroid Adenoma Originated from Supernumerary Gland
title_sort primary hyperparathyroidism due to parathyroid adenoma originated from supernumerary gland
url http://dx.doi.org/10.1155/2018/6482546
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