'Traveling wave'' solutions of Fitzhugh model with cross-diffusion

The FitzHugh-Nagumo equations have been used as a caricatureof the Hodgkin-Huxley equations of neuron FIring and to capture, qualitatively,the general properties of an excitable membrane. In this paper, we utilizea modified version of the FitzHugh-Nagumo equations to model the spatialpropagation of...

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Bibliographic Details
Main Authors: F. Berezovskaya, Erika Camacho, Stephen Wirkus, Georgy Karev
Format: Article
Language:English
Published: AIMS Press 2008-02-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2008.5.239
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Summary:The FitzHugh-Nagumo equations have been used as a caricatureof the Hodgkin-Huxley equations of neuron FIring and to capture, qualitatively,the general properties of an excitable membrane. In this paper, we utilizea modified version of the FitzHugh-Nagumo equations to model the spatialpropagation of neuron firing; we assume that this propagation is (at least,partially) caused by the cross-diffusion connection between the potential andrecovery variables. We show that the cross-diffusion version of the model, be-sides giving rise to the typical fast traveling wave solution exhibited in theoriginal ''diffusion'' FitzHugh-Nagumo equations, additionally gives rise to aslow traveling wave solution. We analyze all possible traveling wave solutionsof the model and show that there exists a threshold of the cross-diffusion coefficient (for a given speed of propagation), which bounds the area where ''normal''impulse propagation is possible.
ISSN:1551-0018