Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult

Ramsay Hunt syndrome associated with varicella zoster virus reactivation affecting the central nervous system is rare. We describe a 55-year-old diabetic female who presented with gait ataxia, right peripheral facial palsy, and painful vesicular lesions involving her right ear. Later, she developed...

Full description

Saved in:
Bibliographic Details
Main Authors: Tommy L. H. Chan, Ana M. Cartagena, Anne Marie Bombassaro, Seyed M. Hosseini-Moghaddam
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2016/9859816
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832566516233535488
author Tommy L. H. Chan
Ana M. Cartagena
Anne Marie Bombassaro
Seyed M. Hosseini-Moghaddam
author_facet Tommy L. H. Chan
Ana M. Cartagena
Anne Marie Bombassaro
Seyed M. Hosseini-Moghaddam
author_sort Tommy L. H. Chan
collection DOAJ
description Ramsay Hunt syndrome associated with varicella zoster virus reactivation affecting the central nervous system is rare. We describe a 55-year-old diabetic female who presented with gait ataxia, right peripheral facial palsy, and painful vesicular lesions involving her right ear. Later, she developed dysmetria, fluctuating diplopia, and dysarthria. Varicella zoster virus was detected in the cerebrospinal fluid by polymerase chain reaction. She was diagnosed with Ramsay Hunt syndrome associated with spread to the central nervous system. Her facial palsy completely resolved within 48 hours of treatment with intravenous acyclovir 10 mg/kg every 8 hours. However, cerebellar symptoms did not improve until a tapering course of steroid therapy was initiated.
format Article
id doaj-art-f32d1c87cbe44c759e7cb51f0402250c
institution Kabale University
issn 1712-9532
1918-1493
language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-f32d1c87cbe44c759e7cb51f0402250c2025-02-03T01:04:02ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932016-01-01201610.1155/2016/98598169859816Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an AdultTommy L. H. Chan0Ana M. Cartagena1Anne Marie Bombassaro2Seyed M. Hosseini-Moghaddam3Department of Clinical Neurological Sciences, London Health Sciences Centre (LHSC), London, ON, CanadaDepartment of Clinical Neurological Sciences, London Health Sciences Centre (LHSC), London, ON, CanadaPharmacy Services, London Health Sciences Centre (LHSC) and Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, CanadaDivision of Infectious Diseases, Department of Medicine, London Health Sciences Centre (LHSC), London, ON, CanadaRamsay Hunt syndrome associated with varicella zoster virus reactivation affecting the central nervous system is rare. We describe a 55-year-old diabetic female who presented with gait ataxia, right peripheral facial palsy, and painful vesicular lesions involving her right ear. Later, she developed dysmetria, fluctuating diplopia, and dysarthria. Varicella zoster virus was detected in the cerebrospinal fluid by polymerase chain reaction. She was diagnosed with Ramsay Hunt syndrome associated with spread to the central nervous system. Her facial palsy completely resolved within 48 hours of treatment with intravenous acyclovir 10 mg/kg every 8 hours. However, cerebellar symptoms did not improve until a tapering course of steroid therapy was initiated.http://dx.doi.org/10.1155/2016/9859816
spellingShingle Tommy L. H. Chan
Ana M. Cartagena
Anne Marie Bombassaro
Seyed M. Hosseini-Moghaddam
Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult
Canadian Journal of Infectious Diseases and Medical Microbiology
title Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult
title_full Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult
title_fullStr Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult
title_full_unstemmed Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult
title_short Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an Adult
title_sort ramsay hunt syndrome associated with central nervous system involvement in an adult
url http://dx.doi.org/10.1155/2016/9859816
work_keys_str_mv AT tommylhchan ramsayhuntsyndromeassociatedwithcentralnervoussysteminvolvementinanadult
AT anamcartagena ramsayhuntsyndromeassociatedwithcentralnervoussysteminvolvementinanadult
AT annemariebombassaro ramsayhuntsyndromeassociatedwithcentralnervoussysteminvolvementinanadult
AT seyedmhosseinimoghaddam ramsayhuntsyndromeassociatedwithcentralnervoussysteminvolvementinanadult