Natural killer cells occupy unique spatial neighborhoods in HER2- and HER2+ human breast cancers
Abstract Tumor-infiltrating lymphocytes are considered clinically beneficial in breast cancer, but the significance of natural killer (NK) cells is less well characterized. As increasing evidence has demonstrated that the spatial organization of immune cells in tumor microenvironments is a significa...
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Main Authors: | Femke A. I. Ehlers, Katie E. Blise, Courtney B. Betts, Shamilene Sivagnanam, Loes F. S. Kooreman, E. Shelley Hwang, Gerard M. J. Bos, Lotte Wieten, Lisa M. Coussens |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Breast Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13058-025-01964-4 |
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