Natural killer cells occupy unique spatial neighborhoods in HER2- and HER2+ human breast cancers

Abstract Tumor-infiltrating lymphocytes are considered clinically beneficial in breast cancer, but the significance of natural killer (NK) cells is less well characterized. As increasing evidence has demonstrated that the spatial organization of immune cells in tumor microenvironments is a significa...

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Bibliographic Details
Main Authors: Femke A. I. Ehlers, Katie E. Blise, Courtney B. Betts, Shamilene Sivagnanam, Loes F. S. Kooreman, E. Shelley Hwang, Gerard M. J. Bos, Lotte Wieten, Lisa M. Coussens
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Breast Cancer Research
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Online Access:https://doi.org/10.1186/s13058-025-01964-4
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