DRESS Syndrome due to Nevirapine Treated with Methylprednisolone

Nevirapine-induced DRESS syndrome is uncommon but a potentially life-threatening condition, with significant morbidity and mortality rates due to multiple-organ involvement. The authors report a case of a 47-year-old HIV-infected female patient who presented with fever, right hypochondrium pain, jau...

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Main Authors: Henrique Pott Junior, Gisele Cristina Gosuen, Ana Cristina Gales
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/269501
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author Henrique Pott Junior
Gisele Cristina Gosuen
Ana Cristina Gales
author_facet Henrique Pott Junior
Gisele Cristina Gosuen
Ana Cristina Gales
author_sort Henrique Pott Junior
collection DOAJ
description Nevirapine-induced DRESS syndrome is uncommon but a potentially life-threatening condition, with significant morbidity and mortality rates due to multiple-organ involvement. The authors report a case of a 47-year-old HIV-infected female patient who presented with fever, right hypochondrium pain, jaundice, and skin rash. The Nevirapine-induced DRESS syndrome was suspected based on clinical presentation and RegiSCAR scoring system. This case highlights the need for a high index of clinical suspicion among HIV-infected patients with severe skin eruption and systemic symptoms.
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series Case Reports in Medicine
spelling doaj-art-f2ee509ed28d4159a2e921bdd2c582872025-02-03T05:54:39ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/269501269501DRESS Syndrome due to Nevirapine Treated with MethylprednisoloneHenrique Pott Junior0Gisele Cristina Gosuen1Ana Cristina Gales2Division of Infectious Diseases, Federal University of São Paulo (UNIFESP), São Paulo, SP, BrazilDivision of Infectious Diseases, Federal University of São Paulo (UNIFESP), São Paulo, SP, BrazilDivision of Infectious Diseases, Federal University of São Paulo (UNIFESP), São Paulo, SP, BrazilNevirapine-induced DRESS syndrome is uncommon but a potentially life-threatening condition, with significant morbidity and mortality rates due to multiple-organ involvement. The authors report a case of a 47-year-old HIV-infected female patient who presented with fever, right hypochondrium pain, jaundice, and skin rash. The Nevirapine-induced DRESS syndrome was suspected based on clinical presentation and RegiSCAR scoring system. This case highlights the need for a high index of clinical suspicion among HIV-infected patients with severe skin eruption and systemic symptoms.http://dx.doi.org/10.1155/2013/269501
spellingShingle Henrique Pott Junior
Gisele Cristina Gosuen
Ana Cristina Gales
DRESS Syndrome due to Nevirapine Treated with Methylprednisolone
Case Reports in Medicine
title DRESS Syndrome due to Nevirapine Treated with Methylprednisolone
title_full DRESS Syndrome due to Nevirapine Treated with Methylprednisolone
title_fullStr DRESS Syndrome due to Nevirapine Treated with Methylprednisolone
title_full_unstemmed DRESS Syndrome due to Nevirapine Treated with Methylprednisolone
title_short DRESS Syndrome due to Nevirapine Treated with Methylprednisolone
title_sort dress syndrome due to nevirapine treated with methylprednisolone
url http://dx.doi.org/10.1155/2013/269501
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