Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer

Aim: To evaluate associations between survival and glycemic control in age-matched patients with endometrial or ovarian cancer, with/without diabetes mellitus (DM). Patients & methods: Patients with newly diagnosed ovarian or endometrial cancer with and without DM were compared. Results: The stu...

Full description

Saved in:
Bibliographic Details
Main Authors: Yael N Kusne, Heidi E Kosiorek, Matthew R Buras, Kyle E Coppola, Patricia M Verona, Curtiss B Cook, Nina J Karlin
Format: Article
Language:English
Published: Taylor & Francis Group 2021-03-01
Series:Future Science OA
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/fsoa-2020-0158
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850153079105650688
author Yael N Kusne
Heidi E Kosiorek
Matthew R Buras
Kyle E Coppola
Patricia M Verona
Curtiss B Cook
Nina J Karlin
author_facet Yael N Kusne
Heidi E Kosiorek
Matthew R Buras
Kyle E Coppola
Patricia M Verona
Curtiss B Cook
Nina J Karlin
author_sort Yael N Kusne
collection DOAJ
description Aim: To evaluate associations between survival and glycemic control in age-matched patients with endometrial or ovarian cancer, with/without diabetes mellitus (DM). Patients & methods: Patients with newly diagnosed ovarian or endometrial cancer with and without DM were compared. Results: The study included 84 patients with ovarian cancer (28, DM); 96 with endometrial cancer (48 with, 48 without DM). DM patients did not have worse overall or progression-free survival than non-DM patients. Glycemic control was not associated with either cancer. Conclusion: There was no association between DM and survival for patients with uterine or ovarian cancer. In addition, there was no association between uterine and ovarian cancer and glycemic control. Additional studies to confirm these observations in larger populations are required.
format Article
id doaj-art-f2e80d8a3fc649c99f19b8f2c0bf6f26
institution OA Journals
issn 2056-5623
language English
publishDate 2021-03-01
publisher Taylor & Francis Group
record_format Article
series Future Science OA
spelling doaj-art-f2e80d8a3fc649c99f19b8f2c0bf6f262025-08-20T02:25:48ZengTaylor & Francis GroupFuture Science OA2056-56232021-03-017310.2144/fsoa-2020-0158Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancerYael N Kusne0Heidi E Kosiorek1Matthew R Buras2Kyle E Coppola3Patricia M Verona4Curtiss B Cook5Nina J Karlin61Department of Internal Medicine, Mayo Clinic Hospital, Phoenix, AZ 85054, USA2Biostatistics, Mayo Clinic Hospital, Phoenix, AZ 85054, USA2Biostatistics, Mayo Clinic Hospital, Phoenix, AZ 85054, USA3Mayo Clinic Cancer Center, Mayo Clinic Hospital, Phoenix, AZ 85054, USA4Enterprise Technology Services, Mayo Clinic Hospital, Phoenix, AZ 85054, USA5Division of Endocrinology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA3Mayo Clinic Cancer Center, Mayo Clinic Hospital, Phoenix, AZ 85054, USAAim: To evaluate associations between survival and glycemic control in age-matched patients with endometrial or ovarian cancer, with/without diabetes mellitus (DM). Patients & methods: Patients with newly diagnosed ovarian or endometrial cancer with and without DM were compared. Results: The study included 84 patients with ovarian cancer (28, DM); 96 with endometrial cancer (48 with, 48 without DM). DM patients did not have worse overall or progression-free survival than non-DM patients. Glycemic control was not associated with either cancer. Conclusion: There was no association between DM and survival for patients with uterine or ovarian cancer. In addition, there was no association between uterine and ovarian cancer and glycemic control. Additional studies to confirm these observations in larger populations are required.https://www.future-science.com/doi/10.2144/fsoa-2020-0158cancermetabolismobstetrics/gynecologyprognostics
spellingShingle Yael N Kusne
Heidi E Kosiorek
Matthew R Buras
Kyle E Coppola
Patricia M Verona
Curtiss B Cook
Nina J Karlin
Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer
Future Science OA
cancer
metabolism
obstetrics/gynecology
prognostics
title Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer
title_full Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer
title_fullStr Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer
title_full_unstemmed Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer
title_short Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer
title_sort mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer
topic cancer
metabolism
obstetrics/gynecology
prognostics
url https://www.future-science.com/doi/10.2144/fsoa-2020-0158
work_keys_str_mv AT yaelnkusne mortalityandglycemiccontrolamongpatientswithdiabetesmellitusanduterineorovariancancer
AT heidiekosiorek mortalityandglycemiccontrolamongpatientswithdiabetesmellitusanduterineorovariancancer
AT matthewrburas mortalityandglycemiccontrolamongpatientswithdiabetesmellitusanduterineorovariancancer
AT kyleecoppola mortalityandglycemiccontrolamongpatientswithdiabetesmellitusanduterineorovariancancer
AT patriciamverona mortalityandglycemiccontrolamongpatientswithdiabetesmellitusanduterineorovariancancer
AT curtissbcook mortalityandglycemiccontrolamongpatientswithdiabetesmellitusanduterineorovariancancer
AT ninajkarlin mortalityandglycemiccontrolamongpatientswithdiabetesmellitusanduterineorovariancancer