Diversity-oriented synthesis of stereodefined tetrasubstituted alkenes via a modular alkyne gem-addition strategy

Abstract Stereocontrolled construction of tetrasubstituted olefins has been an attractive issue yet remains challenging for synthetic chemists. In this manuscript, alkynyl selenides, when treated with ArBCl2, are subject to an exclusive 1,1-carboboration, affording tetrasubstituted alkenes with exce...

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Bibliographic Details
Main Authors: Xuan Di, Sitian Zhou, Yali Qin, Wenjun Li, Yue Zhang, Jie Zhang, Xu Shen, Jie Han, Jin Xie, Hongming Jin
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56184-3
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