TELOMERE LENGTH AND ATHEROSCLEROSIS

The development  and progression of atherosclerosis in most cases takes decades, and at early stages does not present clinically. Multiple studies results witness that telomere   length  reflects  total  grade   of  DNA damage by  the  factors  that  are responsible for atherosclerosis and its compl...

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Main Authors: O. M. Drapkina, R. N. Shepel
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2016-09-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/564
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author O. M. Drapkina
R. N. Shepel
author_facet O. M. Drapkina
R. N. Shepel
author_sort O. M. Drapkina
collection DOAJ
description The development  and progression of atherosclerosis in most cases takes decades, and at early stages does not present clinically. Multiple studies results witness that telomere   length  reflects  total  grade   of  DNA damage by  the  factors  that  are responsible for atherosclerosis and its complications. Velocity of telomeres shortening  increases even before the disease onset  that may play diagnostic  and predictive role.
format Article
id doaj-art-f2c9b852819543e6ba3f493c97146a9f
institution Kabale University
issn 1560-4071
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language Russian
publishDate 2016-09-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-f2c9b852819543e6ba3f493c97146a9f2025-08-20T03:57:26Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202016-09-0109848910.15829/1560-4071-2016-9-84-89522TELOMERE LENGTH AND ATHEROSCLEROSISO. M. Drapkina0R. N. Shepel1National Research Center for Preventive Medicine of the Ministry of Health, MoscowNational Research Center for Preventive Medicine of the Ministry of Health, MoscowThe development  and progression of atherosclerosis in most cases takes decades, and at early stages does not present clinically. Multiple studies results witness that telomere   length  reflects  total  grade   of  DNA damage by  the  factors  that  are responsible for atherosclerosis and its complications. Velocity of telomeres shortening  increases even before the disease onset  that may play diagnostic  and predictive role.https://russjcardiol.elpub.ru/jour/article/view/564atherosclerosistelomerescellular ageingoxidative stress
spellingShingle O. M. Drapkina
R. N. Shepel
TELOMERE LENGTH AND ATHEROSCLEROSIS
Российский кардиологический журнал
atherosclerosis
telomeres
cellular ageing
oxidative stress
title TELOMERE LENGTH AND ATHEROSCLEROSIS
title_full TELOMERE LENGTH AND ATHEROSCLEROSIS
title_fullStr TELOMERE LENGTH AND ATHEROSCLEROSIS
title_full_unstemmed TELOMERE LENGTH AND ATHEROSCLEROSIS
title_short TELOMERE LENGTH AND ATHEROSCLEROSIS
title_sort telomere length and atherosclerosis
topic atherosclerosis
telomeres
cellular ageing
oxidative stress
url https://russjcardiol.elpub.ru/jour/article/view/564
work_keys_str_mv AT omdrapkina telomerelengthandatherosclerosis
AT rnshepel telomerelengthandatherosclerosis